Evidence map›Paper›PMID 37131490›Full record

ArticleNeurobiology of stress2023

Chronic intermittent ethanol exposure disrupts stress-related tripartite communication to impact affect-related behavioral selection in male rats.

J J Munier, S Shen, D Rahal, A Hanna, V N Marty, P R O'Neill, M S Fanselow, I Spigelman

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Neurobiology of stress, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.1field-weighted citation impact, top 56% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Voluntary Ethanol Intake and Anxiety Behavior in Wistar-Uis Rats.International journal of psychological research
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

J J MunierLaboratory of Neuropharmacology, Section of Biosystems & Function, School of Dentistry, UCLA, United States.
S ShenLaboratory of Neuropharmacology, Section of Biosystems & Function, School of Dentistry, UCLA, United States.
D RahalEdna Bennett Pierce Prevention Research Center, The Pennsylvania State University, United States.
A HannaLaboratory of Neuropharmacology, Section of Biosystems & Function, School of Dentistry, UCLA, United States.
V N MartyLaboratory of Neuropharmacology, Section of Biosystems & Function, School of Dentistry, UCLA, United States.
P R O'NeillHatos Center for Neuropharmacology, Department of Psychiatry & Biobehavioral Sciences, David Geffen School of Medicine, UCLA, United States.
M S FanselowDepartment of Psychology, College of Life Sciences, Department of Psychiatry & Biobehavioral Science, David Geffen School of Medicine, UCLA, United States.
I SpigelmanLaboratory of Neuropharmacology, Section of Biosystems & Function, School of Dentistry, UCLA, United States.
Neurobehavioral Systems · USPennsylvania State University · US

Funding

Nociceptin receptor signaling and regulation of dopamine transmission in drug reward circuitryK01DA042219 · NIDA · WASHINGTON UNIVERSITY · PI O'NEILL, PATRICK ROSS · 2017 to 2021
$715k
NIDA NIH HHS K01 DA042219
6 · The paper itself

Abstract

Alcohol use disorder (AUD) is characterized by loss of intake control, increased anxiety, and susceptibility to relapse inducing stressors. Both astrocytes and neurons contribute to behavioral and hormonal consequences of chronic intermittent ethanol (CIE) exposure in animal models. Details on how CIE disrupts hypothalamic neuro-glial communication, which mediates stress responses are lacking. We conducted a behavioral battery (grooming, open field, reactivity to a single, uncued foot-shock, intermittent-access two-bottle choice ethanol drinking) followed by Ca

Identifiers

PMID37131490
PMCPMC10149313
OpenAlexW4366765120

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.