Evidence map›Paper›PMID 37131125›Full record

ArticleBMC nephrology2023

The effect of a novel, digital physical activity and emotional well-being intervention on health-related quality of life in people with chronic kidney disease: trial design and baseline data from a multicentre prospective, wait-list randomised controlled trial (kidney BEAM).

C G Walklin, Hannah M L Young, E Asghari, S Bhandari, R E Billany, N Bishop, K Bramham, J Briggs, J O Burton, J Campbell and 20 more

Registry-linked trialOpen access · goldAbstract readClinical Trial Protocol
PubMed Full text at PMC Publisher
In one paragraph

Article in BMC nephrology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04872933 (Multicentre Prospective Single-blind Wait-list Randomised Controlled Trial, With Nested Pilot, of the Clinical Value and Economic Evaluation of an Online Physical and Emotional Wellbeing Resource for the Improvement of Health-related Quality of Life in People With Chronic Kidney Disease), which is not on this map. Cited by 13 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 1 pooled it
3.8field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04872933 naunknown statusnot on this map

Multicentre Prospective Single-blind Wait-list Randomised Controlled Trial, With Nested Pilot, of the Clinical Value and Economic Evaluation of an Online Physical and Emotional Wellbeing Resource for the Improvement of Health-related Quality of Life in People With Chronic Kidney Disease: The Kidney Beam Trial

TypeinterventionalSponsorKing's College Hospital NHS TrustRan2021 to 2023Enrolled304ConditionsChronic Kidney DiseasesArmsKidney Beam Online Platform
3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 1 synthesis or guideline pooled it, 19 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

30 authors at 20 institutions in 1 country.

C G Walklin *Renal Therapies, King's College Hospital NHS Trust, London, UK.
Hannah M L Young *Leicester Diabetes Centre, Leicester General Hospital, Leicester, UK. hy162@le.ac.uk.
E AsghariDepartment of Nephrology, Guy's and St Thomas' NHS Trust, London, UK.
S BhandariDepartment of Nephrology, Hull University Teaching Hospitals NHS Trust, Hull, UK.
R E BillanyDepartment of Health Sciences, University of Leicester, Leicester, UK.
N BishopSchool of Sport, Exercise and Health Sciences, University of Loughborough, Loughborough, UK.
K BramhamDepartment of Women's Health, King's College London, London, UK.
J BriggsRenal Therapies, King's College Hospital NHS Trust, London, UK.
J O BurtonDepartment of Health Sciences, University of Leicester, Leicester, UK.
J CampbellFaculty of Health, Education and Society, University of Northampton, Northampton, UK.
E M CastleSchool of Physiotherapy, Department of Health Sciences, Brunel University, London, UK.
J ChilcotInstitute of Psychiatry, Psychology & Neuroscience, King's College London, London, UK.
N CooperDepartment of Health Sciences, University of Leicester, Leicester, UK.
V DeelchandDepartment of Nephrology, Royal Free Hospital, London, UK.
M P M Graham-BrownDepartment of Health Sciences, University of Leicester, Leicester, UK.
A HamiltonDepartment of Nephrology, Royal Exeter Hospital, Devon, UK.
M JeskyDepartment of Nephrology, Nottingham NHS Trust, Nottingham, UK.
P A KalraDepartment of Nephrology, Royal Hospital, Northern Care Alliance NHS Foundation Trust, Salford, UK.
P KoufakiDietetics, Nutrition and Biological Sciences, Queen Margaret University, Edinburgh, UK.
K McCaffertyDepartment of Nephrology, Barts Health NHS Trust, London, UK.
A C NixonDepartment of Renal Medicine, Lancashire Teaching Hospitals NHS Foundation Trust, Preston, Lancashire, UK.
H NobleSchool of Nursing and Midwifery, Queen's University, Belfast, UK.
Z L SaynorSchool of Sport, Health and Exercise Science, University of Portsmouth, Portsmouth, UK.
C SothinathanDepartment of Physiotherapy, Chelsea and Westminster NHS Trust, London, UK.
M W TaalCentre for Kidney Research and Innovation, University of Nottingham, Nottingham, UK.
J TollittDepartment of Renal Medicine, University College London, London, UK.
D C WheelerNational Institute of Health Research Leicester Biomedical Research Centre , Leicester, UK.
T J WilkinsonInstitute for Applied Human Physiology, Bangor University, Bangor, Gwynedd, UK.
J H MacdonaldFaculty of life sciences and medicine, King's College London, London, UK.
S A GreenwoodRenal Therapies, King's College Hospital NHS Trust, London, UK.
University of Leicester · GBKing's College Hospital · GBKing's College London · GBBangor University · GBBarts Health NHS Trust · GBBrunel University of London · GBChelsea and Westminster Hospital NHS Foundation Trust · GBGuy's and St Thomas' NHS Foundation Trust · GBLancashire Teaching Hospitals NHS Foundation Trust · GBLeicester General Hospital · GBLoughborough University · GBNIHR Leicester Biomedical Research Centre · GBQueen Margaret University · GBQueen's University Belfast · GBRoyal Devon and Exeter Hospital · GBSalford Royal Hospital · GBThe Royal Free Hospital · GBUniversity College London · GBUniversity of Hull · GBUniversity of Northampton · GB

Funding

NIHR NIHR302926
6 · The paper itself

Abstract

backgroundPhysical activity and emotional self-management has the potential to enhance health-related quality of life (HRQoL), but few people with chronic kidney disease (CKD) have access to resources and support. The Kidney BEAM trial aims to evaluate whether an evidence-based physical activity and emotional wellbeing self-management programme (Kidney BEAM) leads to improvements in HRQoL in people with CKD.

methodsThis was a prospective, multicentre, randomised waitlist-controlled trial, with health economic analysis and nested qualitative studies. In total, three hundred and four adults with established CKD were recruited from 11 UK kidney units. Participants were randomly assigned to the intervention (Kidney BEAM) or a wait list control group (1:1). The primary outcome was the between-group difference in Kidney Disease Quality of Life (KDQoL) mental component summary score (MCS) at 12 weeks. Secondary outcomes included the KDQoL physical component summary score, kidney-specific scores, fatigue, life participation, depression and anxiety, physical function, clinical chemistry, healthcare utilisation and harms. All outcomes were measured at baseline and 12 weeks, with long-term HRQoL and adherence also collected at six months follow-up. A nested qualitative study explored experience and impact of using Kidney BEAM.

results340 participants were randomised to Kidney BEAM (n = 173) and waiting list (n = 167) groups. There were 96 (55%) and 89 (53%) males in the intervention and waiting list groups respectively, and the mean (SD) age was 53 (14) years in both groups. Ethnicity, body mass, CKD stage, and history of diabetes and hypertension were comparable across groups. The mean (SD) of the MCS was similar in both groups, 44.7 (10.8) and 45.9 (10.6) in the intervention and waiting list groups respectively.

conclusionResults from this trial will establish whether the Kidney BEAM self management programme is a cost-effective method of enhancing mental and physical wellbeing of people with CKD.

trial registrationNCT04872933. Registered 5th May 2021.

Indexed as

Quality of LifeRenal Insufficiency, ChronicAdultExerciseFemaleHumansMaleMiddle AgedMulticenter Studies as TopicProspective StudiesRandomized Controlled Trials as TopicTelemedicineWaiting ListsDigital healthe-healthKDQoL-SFMixed-methodsQuality of lifeSF-36Telemedicine

Identifiers

PMID37131125
PMCPMC10152439
OpenAlexW4367834637

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.