Evidence map›Paper›PMID 37130784›Full record

ArticleClinical medicine & research2023

Down-Regulation of the Mineralocorticoid Receptor (MR) and Up-Regulation of Hydroxysteroid 11-Beta Dehydrogenase Type 2 (HSD11B2) Isoenzyme in Critically Ill Patients.

Alice G Vassiliou, Dimitra A Vassiliadi, Chrysi Keskinidou, Edison Jahaj, Efi Botoula, Stylianos Tsagarakis, Anastasia Kotanidou, Ioanna Dimopoulou

Open access · diamondAbstract read
In one paragraph

Article in Clinical medicine & research, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.4field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Alice G Vassiliou1 Department of Critical Care Medicine & Pulmonary Services, National & Kapodistrian University of Athens, "Evangelismos" Hospital, Athens, Greece.
Dimitra A VassiliadiDepartment of Endocrinology, Diabetes and Metabolism, National Expertise Centre for Rare Endocrine Diseases, "Evangelismos" Hospital, Athens, Greece.
Chrysi Keskinidou1 Department of Critical Care Medicine & Pulmonary Services, National & Kapodistrian University of Athens, "Evangelismos" Hospital, Athens, Greece.
Edison Jahaj1 Department of Critical Care Medicine & Pulmonary Services, National & Kapodistrian University of Athens, "Evangelismos" Hospital, Athens, Greece.
Efi BotoulaDepartment of Endocrinology, Diabetes and Metabolism, National Expertise Centre for Rare Endocrine Diseases, "Evangelismos" Hospital, Athens, Greece.
Stylianos TsagarakisDepartment of Endocrinology, Diabetes and Metabolism, National Expertise Centre for Rare Endocrine Diseases, "Evangelismos" Hospital, Athens, Greece.
Anastasia Kotanidou1 Department of Critical Care Medicine & Pulmonary Services, National & Kapodistrian University of Athens, "Evangelismos" Hospital, Athens, Greece.
Ioanna Dimopoulou1 Department of Critical Care Medicine & Pulmonary Services, National & Kapodistrian University of Athens, "Evangelismos" Hospital, Athens, Greece idimo@otenet.gr.
National and Kapodistrian University of Athens · GREvangelismos Hospital · GR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

11-beta-Hydroxysteroid Dehydrogenase Type 2AldosteroneReceptors, MineralocorticoidCritical IllnessDown-RegulationHumansHydrocortisoneHydroxysteroidsIsoenzymesProspective StudiesReninUp-Regulation11-beta-Hydroxysteroid Dehydrogenase Type 2AldosteroneHSD11B2 protein, humanHydrocortisoneHydroxysteroidsIsoenzymesNR3C2 protein, humanReceptors, MineralocorticoidReninAldosteroneCortisolCritical illnessHydroxysteroid 11-beta dehydrogenaseMineralocorticoid receptorNeutrophils

Identifiers

PMID37130784
PMCPMC10153682
OpenAlexW4367728761

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.