Evidence map›Paper›PMID 37129842›Full record

ReviewInfection2023

An appeal for strengthening genomic pathogen surveillance to improve pandemic preparedness and infection prevention: the German perspective.

Bernd Salzberger, Alexander Mellmann, Anna Bludau, Sandra Ciesek, Victor Corman, Alexander Dilthey, Tjibbe Donker, Tim Eckmanns, Richard Egelkamp, Sören G Gatermann and 12 more

Open access · hybridAbstract readReview
In one paragraph

Review in Infection, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.7field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 11 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

22 authors at 13 institutions in 2 countries.

Bernd Salzberger *Department for Infection Control and Infectious Diseases, University Hospital Regensburg, Franz-Josef-Strauß-Allee 11, 93053, Regensburg, Germany. bernd.salzberger@ukr.de.
Alexander Mellmann *Institute for Hygiene, University Hospital Münster, Robert-Koch-Straße 41, 48149, Münster, Germany. mellmann@uni-muenster.de.
Anna BludauDepartment for Infection Control and Infectious Diseases, University Medical Center (UMG), Georg-August University Göttingen, Robert-Koch-Straße 40, 37075, Göttingen, Germany.
Sandra CiesekInstitute of Medical Virology, University Hospital Frankfurt, Goethe University, Frankfurt Am Main, Germany.
Victor CormanInstitute of Virology, Charité Universitätsmedizin Berlin, Berlin, Germany.
Alexander DiltheyInstitute of Medical Microbiology and Hospital Hygiene, University Hospital Düsseldorf, Heinrich-Heine-University Düsseldorf, Düsseldorf, Germany.
Tjibbe DonkerInstitute for Infection Prevention and Hospital Epidemiology, University Medical Center Freiburg, Freiburg, Germany.
Tim EckmannsRobert Koch Institute, Berlin, Germany.
Richard EgelkampNext Generation Sequencing, Public Health Agency of Lower Saxony, Hanover, Germany.
Sören G GatermannDepartment of Medical Microbiology, Ruhr University Bochum, Bochum, Germany.
Hajo GrundmannInstitute for Infection Prevention and Hospital Epidemiology, University Medical Center Freiburg, Freiburg, Germany.
Georg HäckerFaculty of Medicine, Institute of Medical Microbiology and Hygiene, Medical Centre University of Freiburg, Freiburg, Germany.
Martin KaaseDepartment for Infection Control and Infectious Diseases, University Medical Center (UMG), Georg-August University Göttingen, Robert-Koch-Straße 40, 37075, Göttingen, Germany.
Berit LangeDepartment of Epidemiology, Helmholtz Centre for Infection Research, Brunswick, Germany.
Martin MielkeRobert Koch Institute, Berlin, Germany.
Mathias W PletzInstitute of Infectious Diseases and Infection Control, University Hospital, Jena, Germany.
Torsten SemmlerRobert Koch Institute, Berlin, Germany.
Andrea ThürmerRobert Koch Institute, Berlin, Germany.
Lothar H WielerRobert Koch Institute, Berlin, Germany.
Thorsten WolffRobert Koch Institute, Berlin, Germany.
Andreas F Widmer *Division of Infectious Diseases and Hospital Epidemiology, University Hospital Basel, Basel, Switzerland.
Simone Scheithauer *Department for Infection Control and Infectious Diseases, University Medical Center (UMG), Georg-August University Göttingen, Robert-Koch-Straße 40, 37075, Göttingen, Germany. simone.scheithauer@med.uni-goettingen.de.
Robert Koch Institute · DEUniversity of Göttingen · DEUniversity Medical Center Freiburg · DECharité - Universitätsmedizin Berlin · DEDüsseldorf University Hospital · DEGoethe University Frankfurt · DEHelmholtz Centre for Infection Research · DEJena University Hospital · DERuhr University Bochum · DEUniversity Hospital Münster · DEUniversity Hospital of Basel · CHUniversity Hospital Regensburg · DEUniversity of Freiburg · DE

Funding

Bundesministerium für Bildung und Forschung ZMVI1-2518FSB706National University Medicine Research Network on COVID-19 01KX2121
6 · The paper itself

Abstract

The SARS-CoV-2 pandemic has highlighted the importance of viable infection surveillance and the relevant infrastructure. From a German perspective, an integral part of this infrastructure, genomic pathogen sequencing, was at best fragmentary and stretched to its limits due to the lack or inefficient use of equipment, human resources, data management and coordination. The experience in other countries has shown that the rate of sequenced positive samples and linkage of genomic and epidemiological data (person, place, time) represent important factors for a successful application of genomic pathogen surveillance. Planning, establishing and consistently supporting adequate structures for genomic pathogen surveillance will be crucial to identify and combat future pandemics as well as other challenges in infectious diseases such as multi-drug resistant bacteria and healthcare-associated infections. Therefore, the authors propose a multifaceted and coordinated process for the definition of procedural, legal and technical standards for comprehensive genomic pathogen surveillance in Germany, covering the areas of genomic sequencing, data collection and data linkage, as well as target pathogens. A comparative analysis of the structures established in Germany and in other countries is applied. This proposal aims to better tackle epi- and pandemics to come and take action from the "lessons learned" from the SARS-CoV-2 pandemic.

Indexed as

COVID-19Cross InfectionGenomicsHumansPandemicsSARS-CoV-2EpidemiologyGenomicsPandemicSARS-CoV-2Surveillance

Identifiers

PMID37129842
PMCPMC10152431
OpenAlexW4367669401

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.