Evidence map›Paper›PMID 37129468›Full record

ArticleeLife2023

Projected long-term effects of colorectal cancer screening disruptions following the COVID-19 pandemic.

Pedro Nascimento de Lima, Rosita van den Puttelaar, Anne I Hahn, Matthias Harlass, Nicholson Collier, Jonathan Ozik, Ann G Zauber, Iris Lansdorp-Vogelaar, Carolyn M Rutter

Abstract read
In one paragraph

Article in eLife, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Impacts of a Public Health Emergency on Cancer Testing Rates, Follow-up, and Cancer Diagnosis: An Evaluation of the COVID-19 Pandemic.Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology · 2026
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  6. DISTRIBUTED MODEL EXPLORATION WITH EMEWS.Proceedings of the ... Winter Simulation Conference. Winter Simulation Conference · 2024
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

9 authors.

Pedro Nascimento de LimaRAND Corporation, Santa Monica, United States.ORCID 0000-0001-9057-198X
Rosita van den PuttelaarErasmus MC, Rotterdam, Netherlands.ORCID 0000-0003-2216-6557
Anne I HahnMemorial Sloan Kettering Cancer Center, New York, United States.ORCID 0000-0003-4061-2303
Matthias HarlassErasmus MC, Rotterdam, Netherlands.
Nicholson CollierArgonne National Laboratory, Lemont, United States.ORCID 0000-0002-2376-4156
Jonathan OzikArgonne National Laboratory, Lemont, United States.ORCID 0000-0002-3495-6735
Ann G ZauberMemorial Sloan Kettering Cancer Center, New York, United States.ORCID 0000-0002-1764-5994
Iris Lansdorp-VogelaarErasmus MC, Rotterdam, Netherlands.
Carolyn M RutterFred Hutchinson Cancer Center, Seattle, WA, United States.ORCID 0000-0002-4396-8594

Funding

X-RAY CRYSTALLOGRAPHYP30CA008748 · NCI · SLOAN-KETTERING INSTITUTE FOR CANCER RES · PI Hongbiao Carl Lekaye · 1985 to 2026
$347.4M
Comparative Modeling of Effective Policies for Colorectal Cancer ControlU01CA253913 · NCI · SLOAN-KETTERING INST CAN RESEARCH · PI RUTTER, CAROLYN M, ZAUBER, ANN GRAHAM · 2020 to 2025
$6.5M
NCI NIH HHS P30 CA008748NCI NIH HHS U01 CA253913
6 · The paper itself

Abstract

The aftermath of the initial phase of the COVID-19 pandemic may contribute to the widening of disparities in colorectal cancer (CRC) outcomes due to differential disruptions to CRC screening. This comparative microsimulation analysis uses two CISNET CRC models to simulate the impact of ongoing screening disruptions induced by the COVID-19 pandemic on long-term CRC outcomes. We evaluate three channels through which screening was disrupted: delays in screening, regimen switching, and screening discontinuation. The impact of these disruptions on long-term CRC outcomes was measured by the number of life-years lost due to CRC screening disruptions compared to a scenario without any disruptions. While short-term delays in screening of 3-18 months are predicted to result in minor life-years loss, discontinuing screening could result in much more significant reductions in the expected benefits of screening. These results demonstrate that unequal recovery of screening following the pandemic can widen disparities in CRC outcomes and emphasize the importance of ensuring equitable recovery to screening following the pandemic.

Indexed as

Colorectal NeoplasmsCOVID-19Early Detection of CancerHumansPandemicscancer screeningcolorectal cancercomparative modelingCOVID-19epidemiologyglobal healthhumanmicrosimulation

Identifiers

PMID37129468
PMCPMC10154022

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.