Evidence map›Paper›PMID 37129248›Full record

ArticleJournal of proteome research2023

Gestational Diabetes Is Characterized by Decreased Medium-Chain Acylcarnitines and Elevated Purine Degradation Metabolites across Pregnancy: A Case-Control Time-Course Analysis.

Hannah Heath, Rodrigo Rosario, Lauren E McMichael, Rob Fanter, Noemi Alarcon, Adilene Quintana-Diaz, Kari Pilolla, Andrew Schaffner, Elissa Jelalian, Rena R Wing and 3 more

Open access · hybridAbstract read
In one paragraph

Article in Journal of proteome research, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 2 pooled it
4.7field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 2 syntheses or guidelines pooled it, 12 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Review
  4. Article
  5. Article
  6. Article
  7. Multigenerational diabetes mellitus.Frontiers in endocrinology · 2023
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 3 institutions in 2 countries.

Hannah HeathDepartment of Food Science and Nutrition, California Polytechnic State University, San Luis Obispo, California 93407, United States.ORCID 0000-0003-2569-4734
Rodrigo RosarioDepartment of Food Science and Nutrition, California Polytechnic State University, San Luis Obispo, California 93407, United States.
Lauren E McMichaelDepartment of Food Science and Nutrition, California Polytechnic State University, San Luis Obispo, California 93407, United States.
Rob FanterCollege of Agriculture, Food and Environmental Sciences, California Polytechnic State University, San Luis Obispo, California 93407, United States.
Noemi AlarconDepartment of Kinesiology and Public Health, California Polytechnic State University, San Luis Obispo, California 93407, United States.
Adilene Quintana-DiazDepartment of Kinesiology and Public Health, California Polytechnic State University, San Luis Obispo, California 93407, United States.
Kari PilollaDepartment of Food Science and Nutrition, California Polytechnic State University, San Luis Obispo, California 93407, United States.
Andrew SchaffnerCenter for Health Research, California Polytechnic State University, San Luis Obispo, California 93407, United States.
Elissa JelalianDepartment of Psychiatry and Human Behavior, Warren Alpert Medical School at Brown University, Providence, Rhode Island 02903, United States.
Rena R WingDepartment of Psychiatry and Human Behavior, Warren Alpert Medical School at Brown University, Providence, Rhode Island 02903, United States.
Alex BritoLaboratory of Pharmacokinetics and Metabolomic Analysis. Institute of Translational Medicine and Biotechnology. I.M. Sechenov First Moscow State Medical University, 119991 Moscow, Russia.
Suzanne PhelanDepartment of Kinesiology and Public Health, California Polytechnic State University, San Luis Obispo, California 93407, United States.
Michael R La FranoDepartment of Food Science and Nutrition, California Polytechnic State University, San Luis Obispo, California 93407, United States.ORCID 0000-0002-2269-1688
California Polytechnic State University · USBrown University · USSechenov University · RU

Funding

Preventing excessive gestational weight gain in obese womenU01HL114377 · NHLBI · CALIFORNIA POLY STATE U SAN LUIS OBISPO · PI PHELAN, SUZANNE · 2011 to 2016
$4.5M
NHLBI NIH HHS U01 HL114377
6 · The paper itself

Abstract

Gestational Diabetes Mellitus (GDM) results in complications affecting both mothers and their offspring. Metabolomic analysis across pregnancy provides an opportunity to better understand GDM pathophysiology. The objective was to conduct a metabolomics analysis of first and third trimester plasma samples to identify metabolic differences associated with GDM development. Forty pregnant women with overweight/obesity from a multisite clinical trial of a lifestyle intervention were included. Participants who developed GDM (

Indexed as

Diabetes, GestationalCarnitineCase-Control StudiesChromatography, LiquidFemaleHumansPregnancyPurinesTandem Mass SpectrometryacylcarnitineCarnitinePurinesacylcarnitinesfatty acid oxidationgestational diabetes mellitusmetabolomicsomicspurine degradation pathway

Identifiers

PMID37129248
PMCPMC10243101
OpenAlexW4367669648

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.