Evidence map›Paper›PMID 37128912›Full record

ArticleArteriosclerosis, thrombosis, and vascular biology2023

Palmitic Acid-Induced Long Noncoding RNA

Vinay Singh Tanwar, Marpadga A Reddy, Sadhan Das, Vishnu Amaram Samara, Maryam Abdollahi, Suchismita Dey, Vajir Malek, Rituparna Ganguly, Kenneth Stapleton, Linda Lanting and 2 more

Open access · bronzeAbstract read
In one paragraph

Article in Arteriosclerosis, thrombosis, and vascular biology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
4.1field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 17 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Article
  5. Article
  6. CD63Frontiers in cellular and infection microbiology · 2026
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  7. Article
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  10. Review
  11. Article
  12. LncRNATranslational cancer research · 2024
    Article
  13. Review
  14. Epigenomics · 2024
    Article
  15. A New "Lnc" to Brake Inflammation.Arteriosclerosis, thrombosis, and vascular biology · 2023
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

12 authors at 4 institutions in 2 countries.

Vinay Singh TanwarDepartment of Diabetes Complications and Metabolism, Arthur Riggs Diabetes & Metabolism Research Institute (V.S.T., M.A.R., V.A.S., M.A., S.D., V.M., R.G., K.S., L.L., R.N.), Beckman Research Institute of City of Hope, Duarte, CA.ORCID 0000-0001-6168-2752
Marpadga A ReddyDepartment of Diabetes Complications and Metabolism, Arthur Riggs Diabetes & Metabolism Research Institute (V.S.T., M.A.R., V.A.S., M.A., S.D., V.M., R.G., K.S., L.L., R.N.), Beckman Research Institute of City of Hope, Duarte, CA.ORCID 0000-0001-9259-7243
Sadhan DasCurrent affiliation: Department of Biological Sciences, Indian Institute of Science Education and Research Mohali, Punjab, India (S.D.).ORCID 0000-0002-7153-9519
Vishnu Amaram SamaraDepartment of Diabetes Complications and Metabolism, Arthur Riggs Diabetes & Metabolism Research Institute (V.S.T., M.A.R., V.A.S., M.A., S.D., V.M., R.G., K.S., L.L., R.N.), Beckman Research Institute of City of Hope, Duarte, CA.ORCID 0000-0001-5932-0461
Maryam AbdollahiDepartment of Diabetes Complications and Metabolism, Arthur Riggs Diabetes & Metabolism Research Institute (V.S.T., M.A.R., V.A.S., M.A., S.D., V.M., R.G., K.S., L.L., R.N.), Beckman Research Institute of City of Hope, Duarte, CA.ORCID 0000-0002-1989-6068
Suchismita DeyDepartment of Diabetes Complications and Metabolism, Arthur Riggs Diabetes & Metabolism Research Institute (V.S.T., M.A.R., V.A.S., M.A., S.D., V.M., R.G., K.S., L.L., R.N.), Beckman Research Institute of City of Hope, Duarte, CA.
Vajir MalekDepartment of Diabetes Complications and Metabolism, Arthur Riggs Diabetes & Metabolism Research Institute (V.S.T., M.A.R., V.A.S., M.A., S.D., V.M., R.G., K.S., L.L., R.N.), Beckman Research Institute of City of Hope, Duarte, CA.ORCID 0000-0003-3680-058X
Rituparna GangulyDepartment of Diabetes Complications and Metabolism, Arthur Riggs Diabetes & Metabolism Research Institute (V.S.T., M.A.R., V.A.S., M.A., S.D., V.M., R.G., K.S., L.L., R.N.), Beckman Research Institute of City of Hope, Duarte, CA.
Kenneth StapletonDepartment of Diabetes Complications and Metabolism, Arthur Riggs Diabetes & Metabolism Research Institute (V.S.T., M.A.R., V.A.S., M.A., S.D., V.M., R.G., K.S., L.L., R.N.), Beckman Research Institute of City of Hope, Duarte, CA.ORCID 0000-0001-5032-5653
Linda LantingDepartment of Diabetes Complications and Metabolism, Arthur Riggs Diabetes & Metabolism Research Institute (V.S.T., M.A.R., V.A.S., M.A., S.D., V.M., R.G., K.S., L.L., R.N.), Beckman Research Institute of City of Hope, Duarte, CA.
Patrick PirrotteIntegrated Mass Spectrometry Shared Resource, City of Hope Comprehensive Cancer Center, Duarte (P.P.).ORCID 0000-0003-1360-6039
Rama NatarajanDepartment of Diabetes Complications and Metabolism, Arthur Riggs Diabetes & Metabolism Research Institute (V.S.T., M.A.R., V.A.S., M.A., S.D., V.M., R.G., K.S., L.L., R.N.), Beckman Research Institute of City of Hope, Duarte, CA.ORCID 0000-0003-4494-1788
City of Hope · USIndian Institute of Science Education and Research Mohali · INTranslational Genomics Research Institute · USUniversity of Illinois Chicago · US

Funding

Transgenic Mouse FacilityP30CA033572 · NCI · CITY OF HOPE/BECKMAN RESEARCH INSTITUTE · PI XIWEI WU · 1985 to 2026
$86.3M
Inflammatory Gene Transcription In Diabetic ConditionsR01DK065073 · NIDDK · CITY OF HOPE/BECKMAN RESEARCH INSTITUTE · PI NATARAJAN, RAMA · 2003 to 2021
$7.9M
Transcriptional Regulation by Angiotensin II in Vascular Smooth Muscle CellsR01HL106089 · NHLBI · BECKMAN RESEARCH INSTITUTE/CITY OF HOPE · PI NATARAJAN, RAMA · 2011 to 2024
$6.6M
Transforming growth factor beta1, microRNAs, lncRNA and diabetic nephropathyR01DK081705 · NIDDK · BECKMAN RESEARCH INSTITUTE/CITY OF HOPE · PI NATARAJAN, RAMA · 2009 to 2023
$6.1M
NCI NIH HHS P30 CA033572NHLBI NIH HHS R01 HL106089NIDDK NIH HHS R01 DK065073NIDDK NIH HHS R01 DK081705
6 · The paper itself

Abstract

backgroundObesity and diabetes are associated with elevated free fatty acids like palmitic acid (PA), which promote chronic inflammation and impaired inflammation resolution associated with cardiometabolic disorders. Long noncoding RNAs (lncRNAs) are implicated in inflammatory processes; however, their roles in PA-regulated inflammation and resolution are unclear.

methodsWe performed RNA-sequencing analysis to identify PA-regulated coding genes and novel lncRNAs in CD14

resultsTreatment of human CD14

conclusionsUpregulation of

Indexed as

AtherosclerosisRNA, Long NoncodingAnimalsELAV-Like Protein 1HumansInflammationMacrophagesMiceMonocytesNF-kappa BPalmitic AcidRNA-Binding ProteinsELAVL1 protein, humanELAV-Like Protein 1NF-kappa BPalmitic AcidRNA-Binding ProteinsRNA, Long Noncodinginflammationmacrophagesmetabolic diseasesmonocytesRNA, long noncoding

Identifiers

PMID37128912
PMCPMC10287039
OpenAlexW4367182123

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.