Evidence map›Paper›PMID 37128161›Full record

ArticleHIV medicine2023

Intergenerational sex and early sexual debut are associated with HIV infection among transgender women in Paraguay.

Zoilo Morel, Gloria Aguilar, Tania Samudio, Gladys López, Carlos Miguel Rios-González, Liliana Giménez, Christian Schaerer, Santiago Gómez, Teresita Báez, Gladys Estigarribia and 3 more

Open access · bronzeAbstract read
In one paragraph

Article in HIV medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.3field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 6 institutions in 4 countries.

Zoilo MorelFacultad de Ciencias Médicas, Universidad Nacional de Asunción, San Lorenzo, Paraguay.ORCID 0000-0001-6438-446X
Gloria AguilarFacultad de Ciencias Médicas, Universidad Nacional de Asunción, San Lorenzo, Paraguay.
Tania SamudioNational Control Program for HIV/AIDS/STI, Ministry of Public Health and Social Welfare, Asuncion, Paraguay.
Gladys LópezNational Control Program for HIV/AIDS/STI, Ministry of Public Health and Social Welfare, Asuncion, Paraguay.
Carlos Miguel Rios-GonzálezDirección General de Investigación, Universidad Sudamericana, Pedro Juan Caballero, Paraguay.
Liliana GiménezNational Control Program for HIV/AIDS/STI, Ministry of Public Health and Social Welfare, Asuncion, Paraguay.
Christian SchaererPolytechnic School, National University of Asuncion, San Lorenzo, Paraguay.
Santiago GómezFacultad de Ciencias Médicas, Universidad Nacional de Asunción, San Lorenzo, Paraguay.
Teresita BáezDivision Statisticians, Association of Paraguayan Statisticians, Asuncion, Paraguay.
Gladys EstigarribiaRegional Health Research Institute, Universidad Nacional de Caaguazu, Caaguazú, Paraguay.
Julieta MéndezNational Control Program for HIV/AIDS/STI, Ministry of Public Health and Social Welfare, Asuncion, Paraguay.
Sergio MuñozDepartamento de Salud Pública, Universidad de la Frontera, Temuco, Chile.
Willi McFarlandCenter for Public Health Research, San Francisco Department of Public Health, San Francisco, California, USA.
Ministry of Health and Social Welfare · TZUniversidad Nacional de Asunción · PYUniversidad de La Frontera · CLGuyra Paraguay · PYSan Francisco Department of Public Health · USUniversidad Nacional De Caaguazú · PY

Funding

International Traineeships in AIDS Prevention Studies (ITAPS)R25MH123256 · NIMH · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI CHRISTINA P LINDAN · 2020 to 2026
$1.8M
NIMH NIH HHS R25 MH123256
6 · The paper itself

Abstract

introductionHIV prevalence among transgender women is high worldwide. The objectives of the present study were to estimate the current prevalence of HIV and identify factors associated with high HIV burden among transgender women in Paraguay.

methodsTransgender women aged ≥15 years in four regions of Paraguay were recruited by Starfish sampling between February and March 2021.

resultsIn total, 322 transgender women were included. Mean age was 31 years (range 15-67), and 102 had positive HIV test results (31.7%, 95% confidence interval [CI] 26.6-37.1). In multivariable analysis, factors associated with HIV infection were age at first intercourse ≤17 years (adjusted odds ratio [aOR] 5.47; 95% CI 1.05-28.42), >10 years difference in age with the last sexual partner (aOR 1.60; 95% CI 1.04-2.46), substance use (mostly cocaine) (aOR 3.00; 95% CI 1.47-6.12), higher risk perception (aOR 3.08; 95% CI 1.53-6.17), not testing for HIV (aOR 1.23; 95% CI 1.09-1.39), and accessed by a peer educator (aOR 3.86; 95% CI 1.77-8.38).

conclusionsSexual debut as a minor and a large age difference with sexual partners are associated with high burden of HIV among transgender women in Paraguay. Our study corroborates the finding of cocaine use during sex as a risk factor for HIV. Prevention programmes must address structural and social vulnerabilities to stem the tragically high burden of HIV among transgender women.

Indexed as

HIV-1HIV InfectionsHIV SeropositivityTransgender PersonsAdolescentAdultAgedFemaleHumansMaleMiddle AgedParaguayPrevalenceRisk FactorsSexual BehaviorYoung AdultcocaineHIVParaguaysexual behaviourtransgender persons

Identifiers

PMID37128161
PMCPMC10792994
OpenAlexW4367668333

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.