Evidence map›Paper›PMID 37128146›Full record

ArticleBrain and behavior2023

Clinical features of ischemic stroke in patients with nonvalvular atrial fibrillation combined with intracranial atherosclerotic stenosis.

Ning Wu, Xinli Wang, Shuai Jia, Xiaomei Cui, Yaozhen Wang, Jian Li, Xiaojun Zhang, Yanqiang Wang

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Brain and behavior, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.1field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 5 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Ning WuDepartment of Neurology II, Affiliated Hospital of Weifang Medical University, Weifang, Shandong, China.ORCID 0000-0003-1428-7703
Xinli WangDepartment of Neurorehabilitation, Yidu Central Hospital of Weifang, Weifang, Shandong, China.
Shuai JiaDepartment of Neurology II, Affiliated Hospital of Weifang Medical University, Weifang, Shandong, China.
Xiaomei CuiDepartment of Neurology II, Affiliated Hospital of Weifang Medical University, Weifang, Shandong, China.
Yaozhen WangDepartment of Neurology II, Affiliated Hospital of Weifang Medical University, Weifang, Shandong, China.
Jian LiDepartment of Neurology II, Affiliated Hospital of Weifang Medical University, Weifang, Shandong, China.
Xiaojun ZhangDepartment of Neurology II, Affiliated Hospital of Weifang Medical University, Weifang, Shandong, China.
Yanqiang WangDepartment of Neurology II, Affiliated Hospital of Weifang Medical University, Weifang, Shandong, China.
Weifang Medical University · CNYidu Central Hospital of Weifang · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundNonvalvular atrial fibrillation (NVAF) and intracranial atherosclerotic stenosis (ICAS) are major causes of ischemic stroke. Relatively few studies have focused on the risk factors and clinical features of ischemic stroke caused by NVAF combined with ICAS.

methodWe retrospectively evaluated NVAF and/or ICAS in patients with acute ischemic stroke admitted within 72 h after stroke. All patients with acute ischemic stroke underwent diffusion-weighted magnetic resonance imaging (DWI), magnetic resonance angiography (MRA), computed tomography angiography (CTA), and/or digital subtraction angiography (DSA). NVAF was detected by routine electrocardiogram or 24-h Holter examination, Doppler echocardiography, and contrast echocardiography of the right heart.

resultsAmong the 635 enrolled patients, NVAF, ICAS, and NVAF+ICAS were diagnosed in 170 (26.77%), 255 (40.16%), and 210 (33.07%) patients, respectively. Patients in the NVAF+ICAS group were older (p < .001), specifically aged ≥75 years (p < .001). The admission time of the NVAF+ICAS group was shorter (p < .001) than that of the ICAS group. The admission NIHSS score of the NVAF group was higher than that of the NVAF+ICAS group (p < .001). HsCRP, NTpro-BNP, and LEVF levels were significantly different among the three groups (p < .001). NVAF+ICAS ischemic stroke occurred mainly in the right hemisphere (52.4%).

conclusionNVAF with ICAS ischemic stroke is more likely to occur in older patients. Infarctions occurred mainly in the right cerebral hemisphere. Neurological deficits in NVAF are more severe than those in NVAF combined with ICAS and in simple ICAS ischemic strokes. HsCRP, LEVF, andNTpro-BNP seem to be closely associated with NVAF+ICAS ischemic stroke.

Indexed as

Atrial FibrillationIntracranial ArteriosclerosisIschemic StrokeStrokeAgedConstriction, PathologicC-Reactive ProteinHumansRetrospective StudiesRisk FactorsC-Reactive Proteinclinical characteristicintracranial atherosclerotic stenosis (ICAS)ischemic strokenonvalvular atrial fibrillation (NVAF)pathogenesisrisk factors

Identifiers

PMID37128146
PMCPMC10275557
OpenAlexW4367668320

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.