Evidence map›Paper›PMID 37128029›Full record

ArticleNature food2020

A natural mutation in Pisum sativum L. (pea) alters starch assembly and improves glucose homeostasis in humans.

Katerina Petropoulou, Louise J Salt, Cathrina H Edwards, Frederick J Warren, Isabel Garcia-Perez, Edward S Chambers, Rasha Alshaalan, Mai Khatib, Natalia Perez-Moral, Kathryn L Cross and 19 more

Open access · greenAbstract read
PubMed Publisher
In one paragraph

Article in Nature food, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 2 pooled it
4.0field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 2 syntheses or guidelines pooled it, 58 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Trial
  4. Trial
  5. Trial
  6. Review
  7. A Suite of Pea (International journal of molecular sciences · 2025
    Article
  8. Article
  9. Article
  10. Review
  11. Article
  12. Article
  13. Review
  14. Frontiers in nutrition · 2022
    Article
  15. Article
  16. Article
  17. Article
  18. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

29 authors at 8 institutions in 3 countries.

Katerina Petropoulou *Section for Nutrition Research, Department of Metabolism, Digestion and Reproduction, Faculty of Medicine, Imperial College London, London, UK.ORCID http://orcid.org/0000-0003-4680-9246
Louise J Salt *Quadram Institute Bioscience, Norwich, UK.
Cathrina H Edwards *Quadram Institute Bioscience, Norwich, UK.ORCID http://orcid.org/0000-0003-4952-0229
Frederick J Warren *Quadram Institute Bioscience, Norwich, UK.
Isabel Garcia-PerezComputational and Systems Medicine, Division of Integrated Systems Medicine and Digestive Diseases, Department of Surgery and Cancer, Faculty of Medicine, Imperial College London, London, UK.ORCID http://orcid.org/0000-0001-8398-0603
Edward S ChambersSection for Nutrition Research, Department of Metabolism, Digestion and Reproduction, Faculty of Medicine, Imperial College London, London, UK.ORCID http://orcid.org/0000-0001-7074-1312
Rasha AlshaalanSection for Nutrition Research, Department of Metabolism, Digestion and Reproduction, Faculty of Medicine, Imperial College London, London, UK.
Mai KhatibSection for Nutrition Research, Department of Metabolism, Digestion and Reproduction, Faculty of Medicine, Imperial College London, London, UK.
Natalia Perez-MoralQuadram Institute Bioscience, Norwich, UK.
Kathryn L CrossQuadram Institute Bioscience, Norwich, UK.
Lee KellingrayQuadram Institute Bioscience, Norwich, UK.
Rachael StanleyQuadram Institute Bioscience, Norwich, UK.
Todor KoevQuadram Institute Bioscience, Norwich, UK.
Yaroslav Z KhimyakSchool of Pharmacy, University of East Anglia, Norwich, UK.ORCID http://orcid.org/0000-0003-0424-4128
Arjan NarbadQuadram Institute Bioscience, Norwich, UK.
Nicholas PenneyComputational and Systems Medicine, Division of Integrated Systems Medicine and Digestive Diseases, Department of Surgery and Cancer, Faculty of Medicine, Imperial College London, London, UK.ORCID http://orcid.org/0000-0003-0896-6590
Jose Ivan Serrano-ContrerasComputational and Systems Medicine, Division of Integrated Systems Medicine and Digestive Diseases, Department of Surgery and Cancer, Faculty of Medicine, Imperial College London, London, UK.ORCID http://orcid.org/0000-0001-8669-7571
Maria N CharalambidesDepartment of Mechanical Engineering, Imperial College London, London, UK.ORCID http://orcid.org/0000-0002-9262-3357
Jesus Miguens BlancoDivision of Integrative Systems Medicine and Digestive Disease, Department of Metabolism, Digestion and Reproduction, Imperial College London, London, UK.
Rocio Castro SeoaneDivision of Integrative Systems Medicine and Digestive Disease, Department of Metabolism, Digestion and Reproduction, Imperial College London, London, UK.
Julie A K McDonaldMRC Centre for Molecular Bacteriology and Infection, Imperial College London, London, UK.ORCID http://orcid.org/0000-0003-0739-6047
Julian R MarchesiDivision of Integrative Systems Medicine and Digestive Disease, Department of Metabolism, Digestion and Reproduction, Imperial College London, London, UK.
Elaine HolmesSection for Nutrition Research, Department of Metabolism, Digestion and Reproduction, Faculty of Medicine, Imperial College London, London, UK.ORCID http://orcid.org/0000-0002-0556-8389
Ian F GodslandDiabetes, Endocrinology and Metabolism, Department of Medicine, Imperial College London, London, UK.ORCID http://orcid.org/0000-0002-0606-465X
Douglas J Morrison *Scottish Universities Environmental Research Centre, University of Glasgow, East Kilbride, UK.ORCID http://orcid.org/0000-0002-4161-5699
Tom Preston *Scottish Universities Environmental Research Centre, University of Glasgow, East Kilbride, UK.ORCID http://orcid.org/0000-0002-9900-5682
Claire Domoney *John Innes Centre, Norwich, UK.
Peter J Wilde *Quadram Institute Bioscience, Norwich, UK.
Gary S Frost *Section for Nutrition Research, Department of Metabolism, Digestion and Reproduction, Faculty of Medicine, Imperial College London, London, UK. g.frost@imperial.ac.uk.ORCID http://orcid.org/0000-0003-0529-6325
Imperial College London · GBQuadram Institute · GBScottish Universities Environmental Research Centre · GBUniversity of East Anglia · GBJohn Innes Centre · GBKing Abdulaziz University · SAMurdoch University · AUPrincess Nourah bint Abdulrahman University · SA

Funding

Biotechnology and Biological Sciences Research Council BB/L025418/1Biotechnology and Biological Sciences Research Council BBS/E/J/000CA392Medical Research Council MR/P028225/1
6 · The paper itself

Abstract

Elevated postprandial glucose (PPG) is a significant risk factor for non-communicable diseases globally. Currently, there is a limited understanding of how starch structures within a carbohydrate-rich food matrix interact with the gut luminal environment to control PPG. Here, we use pea seeds (Pisum sativum) and pea flour, derived from two near-identical pea genotypes (BC1/19RR and BC1/19rr) differing primarily in the type of starch accumulated, to explore the contribution of starch structure, food matrix and intestinal environment to PPG. Using stable isotope

Identifiers

PMID37128029
OpenAlexW3095880399

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.