Evidence map›Paper›PMID 37127908›Full record

ArticleAmerican journal of epidemiology2023

Investigating the Shape and Strength of the Relationship Between Maternal Weight Gain and Gestational Age at Delivery in Twin and Singleton Pregnancies.

Michelle C Dimitris, Jennifer A Hutcheon, Robert W Platt, Michal Abrahamowicz, Marie-Eve Beauchamp, Katherine P Himes, Lisa M Bodnar, Jay S Kaufman

Open access · greenAbstract read
In one paragraph

Article in American journal of epidemiology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.6field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 2 countries.

Michelle C Dimitris
Jennifer A Hutcheon
Robert W Platt
Michal Abrahamowicz
Marie-Eve Beauchamp
Katherine P Himes
Lisa M Bodnar
Jay S Kaufman
McGill University · CAUniversity of Pittsburgh · USMcGill University Health Centre · CAUniversity of British Columbia · CA

Funding

Innovative Approaches to Inform Evidence-Based Pregnancy Weight Gain GuidelinesR01HD072008 · NICHD · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI BODNAR, LISA M, HUTCHEON, JENNIFER ANNE · 2013 to 2016
$2.4M
Innovative approaches to inform evidence-based pregnancy weight gain guidelinesR01HD094777 · NICHD · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI BODNAR, LISA M, HUTCHEON, JENNIFER ANNE · 2018 to 2021
$2.1M
Informing Evidence-based Maternal Weight Gain Guidelines for Twin PregnanciesR01NR014245 · NINR · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI BODNAR, LISA M, HUTCHEON, JENNIFER ANNE · 2013 to 2016
$1.9M
NICHD NIH HHS R01 HD072008NICHD NIH HHS R01 HD094777NINR NIH HHS R01 NR014245
6 · The paper itself

Abstract

Both inadequate and excessive maternal weight gain are correlated with preterm delivery in singleton pregnancies, yet this relationship has not been adequately studied in twins. We investigated the relationship between time-varying maternal weight gain and gestational age at delivery in twin pregnancies and compared it with that in singletons delivered in the same study population. We used serial weight measurements abstracted from charts for twin and singleton pregnancies delivered during 1998-2013 in Pittsburgh, Pennsylvania. Our exposure was time-varying weight gain z score, calculated using gestational age-standardized and prepregnancy body mass index-stratified twin- and singleton-specific charts, and our outcome was gestational age at delivery. Our analyses used a flexible extension of the Cox proportional hazards model that allowed for nonlinear and time-dependent effects. We found a U-shaped relationship between weight gain z score and gestational age at delivery among twin pregnancies (lowest hazard of delivery observed at z score = 1.2), which we attributed to increased hazard of early preterm spontaneous delivery among pregnancies with low weight gain and increased hazard of late preterm delivery without labor among pregnancies with high weight gain. Our findings may be useful for updating provisional guidelines for maternal weight gain in twin pregnancies.

Indexed as

Gestational Weight GainPremature BirthFemaleGestational AgeHumansInfant, NewbornPregnancyPregnancy OutcomePregnancy, TwinRetrospective StudiesWeight Gaingestational weight gainpregnancypreterm deliverysurvival analysistime-to-event analysistwin pregnancy

Identifiers

PMID37127908
PMCPMC10988224
OpenAlexW4367668803

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.