ReviewNature microbiology2023
The virome of the last eukaryotic common ancestor and eukaryogenesis.
Review in Nature microbiology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers.
What it found
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Who cites it
36 citing papers in PubMed, 51 citations in OpenAlex.
- Infection cycles of viruses of the phylum Nucleocytoviricota.Nature reviews. Microbiology · 2026Review
- Article
- Metagenomic Insights Into Red Sea Biodiversity Across the Web of Life.Environmental microbiology · 2026Article
- Article
- Article
- Diversity, ecology, cell biology and evolution of the Asgard archaea.Nature reviews. Microbiology · 2026Review
- The archaeal roots of eukaryotic life.Proceedings of the National Academy of Sciences of the United States of America · 2026Article
- Reassessing viral origins and evolutionary placement in the tree of life.Antonie van Leeuwenhoek · 2026Review
- Article
- Strain-level diversity of giant viruses infecting chlorarachniophyte algae in the subtropical North Pacific.The ISME journal · 2026Article
- Endogenized polinton-like viruses in the dinoflagellateThe Journal of general virology · 2025Article
- Cryo-EM resolves the structure of the archaeal dsDNA virus HFTV1 from head to tail.Science advances · 2025Article
- A novel mobile genetic element with virus-like characteristics is widespread in the world's oceans.bioRxiv : the preprint server for biology · 2025Article
- Review
- Ancient Host-Virus Gene Transfer Hints at a Diverse Pre-LECA Virosphere.Journal of molecular evolution · 2025Article
- Horizontal transmission of functionally diverse transposons is a major source of new introns.Proceedings of the National Academy of Sciences of the United States of America · 2025Article
- Article
- Host-Calibrated Time Tree Caps the Age of Giant Viruses.Molecular biology and evolution · 2025Article
- Human Riboviruses: A Comprehensive Study.Journal of molecular evolution · 2025Review
- The nucleocapsid architecture and structural atlas of the prototype baculovirus define the hallmarks of a new viral realm.Science advances · 2024Article
Corrections and comments
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Authors and funding
3 authors at 3 institutions in 2 countries.
Funding
Abstract
All extant eukaryotes descend from the last eukaryotic common ancestor (LECA), which is thought to have featured complex cellular organization. To gain insight into LECA biology and eukaryogenesis-the origin of the eukaryotic cell, which remains poorly understood-we reconstructed the LECA virus repertoire. We compiled an inventory of eukaryotic hosts of all major virus taxa and reconstructed the LECA virome by inferring the origins of these groups of viruses. The origin of the LECA virome can be traced back to a small set of bacterial-not archaeal-viruses. This provenance of the LECA virome is probably due to the bacterial origin of eukaryotic membranes, which is most compatible with two endosymbiosis events in a syntrophic model of eukaryogenesis. In the first endosymbiosis, a bacterial host engulfed an Asgard archaeon, preventing archaeal viruses from entry owing to a lack of archaeal virus receptors on the external membranes.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.