Evidence map›Paper›PMID 37127677›Full record

ReviewCell death discovery2023

Vascular endothelium is the basic way for stem cells to treat erectile dysfunction: a bibliometric study.

Hede Zou, Xuesong Zhang, Wenkang Chen, Yi Tao, Bolin Li, Hanfei Liu, Ruikun Wang, Jiayou Zhao

Open access · goldAbstract readReview
In one paragraph

Review in Cell death discovery, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 1 pooled it
5.8field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 1 synthesis or guideline pooled it, 26 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Androgens are a Key Factor Affecting Immune Related Diseases.The world journal of men's health · 2026
    Review
  4. Article
  5. Article
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  7. Review
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  10. Article
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  15. Decreased expression ofAmerican journal of clinical and experimental urology · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Hede Zou *Graduate School, China Academy of Chinese Medical Sciences, Beijing, China.ORCID http://orcid.org/0000-0002-8894-6786
Xuesong Zhang *Guang'anmen Hospital, China Academy of Chinese Medical Sciences, Beijing, China.
Wenkang Chen *Graduate School, China Academy of Chinese Medical Sciences, Beijing, China.
Yi Tao *Tianjin University of Traditional Chinese Medicine, Tianjin, China.
Bolin LiGraduate School, China Academy of Chinese Medical Sciences, Beijing, China.
Hanfei LiuHebei University of Chinese Medicine, Shijiazhuang, Hebei, China.
Ruikun WangHebei University of Chinese Medicine, Shijiazhuang, Hebei, China.
Jiayou ZhaoGraduate School, China Academy of Chinese Medical Sciences, Beijing, China. zhaojiayou520@126.com.ORCID http://orcid.org/0000-0002-1686-4212
Chinese Academy of Medical Sciences & Peking Union Medical College · CNHebei University of Chinese Medicine · CNTianjin University of Traditional Chinese Medicine · CN

Funding

National Natural Science Foundation of China (National Science Foundation of China) 82274337
6 · The paper itself

Abstract

Vascular endothelial is considered to be a key factor in the pathogenesis of erectile dysfunction (ED). The purpose is to reveal the research trend of the field of ED and vascular endothelium. In addition, the goal is to discover the role and mechanism of vascular endothelium in ED. Bibliometrics and visualization methods based on CiteSpace were selected. We conducted the co-authorship analysis of countries, institutions and authors, co-occurrence analysis of keywords, and co-citation analysis of literature and authors through CiteSpace 6.1.R3. 1431 articles from Web of Science Core Collection (WOSCC) were included in the analysis from 1991 to 2022. We found some influential and cutting-edge nodes in each map, including countries, institutions, authors, articles, etc. Stem cell, therapy, oxidative stress, cavernous nerve injury, radical prostatectomy, fibrosis, erectile function, mesenchymal stem cell, and apoptosis may be hot keywords. In conclusion, the efficacy and mechanisms of stem cells and their derivatives in the treatment of diabetes (DM) ED and cavernous nerve injury (CNI) ED are the future research trends. Stem cells therapy for ED is a hot spot in this field, which side notes that stem cells may work mainly through improving endothelial function. Vascular endothelial cells and VEGF may repair nerve and cavernous smooth muscle directly or indirectly, and finally polish up erectile function.

Identifiers

PMID37127677
PMCPMC10151332
OpenAlexW4367597908

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.