Evidence map›Paper›PMID 37127275›Full record

ArticleThe American journal of tropical medicine and hygiene2023

Older Age in Subarachnoid Neurocysticercosis Reflects a Long Prepatent Period.

Fernando Nateros, Edith Saenz, Herbert Saavedra, Isidro Gonzales, E Javier Pretell, Erika Perez, Yesenia Castillo, Javier A Bustos, Hector H Garcia, Cysticercosis Working Group in Peru

Open access · greenAbstract read
In one paragraph

Article in The American journal of tropical medicine and hygiene, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.8field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 7 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 1 country.

Fernando NaterosFacultad de Medicina Alberto Hurtado, Universidad Peruana Cayetano Heredia, Lima, Peru.
Edith SaenzCentro Básico de Investigación en Exámenes Auxiliares en Parasitosis del Sistema Nervioso Central, Instituto Nacional de Ciencias Neurológicas, Lima, Peru.
Herbert SaavedraCentro Básico de Investigación en Exámenes Auxiliares en Parasitosis del Sistema Nervioso Central, Instituto Nacional de Ciencias Neurológicas, Lima, Peru.
Isidro GonzalesCentro Básico de Investigación en Exámenes Auxiliares en Parasitosis del Sistema Nervioso Central, Instituto Nacional de Ciencias Neurológicas, Lima, Peru.
E Javier PretellHospital Nacional Alberto Sabogal, Callao, Peru.
Erika PerezCentro Básico de Investigación en Exámenes Auxiliares en Parasitosis del Sistema Nervioso Central, Instituto Nacional de Ciencias Neurológicas, Lima, Peru.
Yesenia CastilloCentro de Salud Global, Universidad Peruana Cayetano Heredia, Lima, Peru.
Javier A BustosCentro Básico de Investigación en Exámenes Auxiliares en Parasitosis del Sistema Nervioso Central, Instituto Nacional de Ciencias Neurológicas, Lima, Peru.
Hector H GarciaCentro Básico de Investigación en Exámenes Auxiliares en Parasitosis del Sistema Nervioso Central, Instituto Nacional de Ciencias Neurológicas, Lima, Peru.
Cysticercosis Working Group in Peru
Instituto Nacional de Enfermedades Neoplásicas · PEInstituto Nacional de Ciencias NeurológicasNational University of Callao · PEUniversidad Peruana Cayetano Heredia · PE

Funding

Training in Parasitic Diseases and Central Nervous System Infections in Peru.D43TW001140 · FIC · UNIVERSIDAD PERUANA CAYETANO HEREDIA · PI GARCIA, HECTOR HUGO, GILMAN, ROBERT H · 1999 to 2025
$5.7M
Combined Albendazole and Praziquantel in Subarachnoid NCC, CCC, Lead applicationU01NS086974 · NINDS · UNIVERSIDAD PERUANA CAYETANO HEREDIA · PI BUSTOS, JAVIER A · 2015 to 2020
$2.2M
FIC NIH HHS D43 TW001140NINDS NIH HHS U01 NS086974
6 · The paper itself

Abstract

Patients with subarachnoid neurocysticercosis (NCC) are usually older than those with parenchymal disease. Whether this difference reflects a prolonged presymptomatic period or a delay in diagnosis is not clear. From 408 eligible patients, we retrospectively compared the age at symptom onset in 140 patients diagnosed with parenchymal (pure viable or pure calcified) and subarachnoid NCC who had a confirmatory image available not more than 2 years after the beginning of symptoms. Patients with mixed (parenchymal and subarachnoid) NCC or those with parenchymal cysts at different stages (viable and/or degenerating and/or calcified) were not included. After controlling by sex and residence in rural endemic regions, the mean age at symptom onset in patients with subarachnoid disease was 13.69 years older than those with viable parenchymal disease. A long incubation period is a major contributing factor to older age at presentation in subarachnoid NCC, independent of delayed diagnosis or access to care.

Indexed as

CystsNeurocysticercosisAdolescentAgedHumansRetrospective StudiesRural PopulationSubarachnoid Space

Identifiers

PMID37127275
PMCPMC10540123
OpenAlexW4367596362

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.