Evidence map›Paper›PMID 37126691›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2023

Intestinal bile acids provide a surmountable barrier against

Simoun Icho, Jennifer S Ward, John Tam, Larry K Kociolek, Casey M Theriot, Roman A Melnyk

Open access · hybridAbstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
2.7field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 14 citations in OpenAlex.

  1. Trial
  2. Review
  3. Article
  4. Article
  5. Effects of Bile on PathogenicBiomolecules · 2025
    Article
  6. Article
  7. Review
  8. Article
  9. Rapid discrimination between clinicalFrontiers in microbiology · 2024
    Article
  10. Article
  11. The microbial derived bile acid lithocholate and its epimers inhibitbioRxiv : the preprint server for biology · 2023
    Article
  12. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 2 countries.

Simoun IchoMolecular Medicine Program, The Hospital for Sick Children Research Institute, Toronto, ON M5G 0A4.
Jennifer S WardMolecular Medicine Program, The Hospital for Sick Children Research Institute, Toronto, ON M5G 0A4.
John TamMolecular Medicine Program, The Hospital for Sick Children Research Institute, Toronto, ON M5G 0A4.
Larry K KociolekAnn & Robert H. Lurie, Children's Hospital of Chicago, Chicago, IL 60611.
Casey M TheriotDepartment of Population Health and Pathobiology, College of Veterinary Medicine, North Carolina State University, Raleigh, NC 27606.ORCID 0000-0002-1895-8941
Roman A MelnykMolecular Medicine Program, The Hospital for Sick Children Research Institute, Toronto, ON M5G 0A4.ORCID 0000-0002-7187-2362
University of Toronto · CAHospital for Sick Children · CANorth Carolina State University · USNorthwestern University · US

Funding

CIHR PJ
6 · The paper itself

Abstract

Intestinal bile acids play an essential role in the

Indexed as

Bacterial ToxinsClostridioides difficileClostridium InfectionsAnimalsBacterial ProteinsBile Acids and SaltsHumansIntestinesMiceBacterial ProteinsBacterial ToxinsBile Acids and Saltsbile acidC. difficileHostpathogenesisToxin

Identifiers

PMID37126691
PMCPMC10175849
OpenAlexW4367623768

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.