Evidence map›Paper›PMID 37126386›Full record

Trial reportJournal of medical Internet research2023

Efficacy of Web-Based, Guided Self-help Cognitive Behavioral Therapy-Enhanced for Binge Eating Disorder: Randomized Controlled Trial.

Bernou Melisse, Elske van den Berg, Margo de Jonge, Matthijs Blankers, Eric van Furth, Jack Dekker, Edwin de Beurs

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in Journal of medical Internet research, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 3 syntheses or guidelines pooled it.

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  8. A Multi-Site Study of Brief Cognitive-Behavioural Therapy for Eating Disorders for Individuals With BMI ≥ 30.European eating disorders review : the journal of the Eating Disorders Association · 2026
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  9. Design, Implement, Sustain: Advancing Program-Led Interventions for Binge Eating, a Narrative Review.European eating disorders review : the journal of the Eating Disorders Association · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Bernou MelisseNovarum Center for Eating Disorders, Amstelveen, Netherlands.ORCID 0000-0003-2636-5262
Elske van den BergNovarum Center for Eating Disorders, Amstelveen, Netherlands.ORCID 0000-0002-3889-9897
Margo de JongeNovarum Center for Eating Disorders, Amstelveen, Netherlands.ORCID 0000-0002-5144-1119
Matthijs BlankersResearch Department, Arkin Mental Health Institute, Amsterdam, Netherlands.ORCID 0000-0002-8821-3312
Eric van FurthDepartment of Psychiatry, Leiden University Medical Center, Leiden, Netherlands.ORCID 0000-0002-1131-0886
Jack DekkerResearch Department, Arkin Mental Health Institute, Amsterdam, Netherlands.ORCID 0000-0003-3782-6431
Edwin de BeursSection Clinical Psychology, Leiden University, Leiden, Netherlands.ORCID 0000-0003-3832-8477

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundOwing to the gap between treatment supply and demand, there are long waiting periods for patients with binge eating disorder, and there is an urgent need to increase their access to specialized treatment. Guided self-help cognitive behavioral therapy-enhanced (CBT-E) may have great advantages for patients if its efficacy can be established.

objectiveThe aim of this study was to examine the efficacy of guided self-help CBT-E compared with that of a delayed-treatment control condition.

methodsA single-blind 2-arm randomized controlled trial was designed to evaluate guided self-help CBT-E according to an intention-to-treat analysis. A total of 180 patients were randomly assigned to guided self-help CBT-E (n=90, 50%) or the delayed-treatment control condition (n=90, 50%) for which guided self-help CBT-E was provided after the initial 12-week delay. The primary outcome was reduction in binges. The secondary outcome was full recovery at the end of treatment, as measured using the Eating Disorder Examination during the last 4 weeks of treatment. A linear mixed model analysis was performed to compare treatment outcomes at the end of treatment. A second linear mixed model analysis was performed to measure between- and within-group effects for up to 24 weeks of follow-up. The Eating Disorder Examination-Questionnaire and clinical impairment assessment were conducted before and after treatment and during follow-up. In addition, dropout rates were assessed in both conditions.

resultsDuring the last 4 weeks of treatment, objective binges reduced from an average of 19 (SD 16) to 3 (SD 5) binges, and 40% (36/90) showed full recovery in the guided self-help CBT-E group. Between-group effect size (Cohen d) was 1.0 for objective binges. At follow-up, after both groups received treatment, there was no longer a difference between the groups. Of the 180 participants, 142 (78.9%) completed treatment. The overall treatment dropout appeared to be associated with gender, level of education, and number of objective binges at baseline but not with treatment condition.

conclusionsThis is the first study to investigate the efficacy of guided self-help CBT-E. Guided self-help CBT-E appeared to be an efficacious treatment. This study's findings underscore the international guidelines recommending this type of treatment for binge eating disorder.

trial registrationNetherlands Trial Registry (NTR) NL7994; https://trialsearch.who.int/Trial2.aspx?TrialID=NL7994. INTERNATIONAL REGISTERED REPORT IDENTIFIER (IRRID): RR2-10.1186/s12888-020-02604-1.

Indexed as

Binge-Eating DisorderCognitive Behavioral TherapyInternet-Based InterventionSelf CareAdultFemaleHumansMaleSample SizeSingle-Blind MethodSurveys and QuestionnairesTime FactorsTime-to-TreatmentTreatment Adherence and ComplianceTreatment OutcomeBEDbinge eating disorderCBT-Ecognitive behavioral therapy–enhancedguided self-helprandomized controlled trialRCT

Identifiers

PMID37126386
PMCPMC10186189

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.