ArticleClinical oral investigations2023
Biological properties of Ceraputty as a retrograde filling material: an in vitro study on hPDLSCs.
Article in Clinical oral investigations, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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Who cites it
9 citing papers in PubMed, 12 citations in OpenAlex.
- Cytotoxicity and Bioactivity of Five Hydraulic Silicate Cements in Human Dental Pulp Cells at Different Setting Stages.International dental journal · 2026Article
- Effects of sodium hypochlorite and chlorhexidine on microhardness and solubility of mineral trioxide aggregate and bioceramic putty.Journal of conservative dentistry and endodontics · 2026Article
- Laboratory Evaluation of the Physicochemical Properties of Novel Pre-Mixed Putty-Type Bioceramic Materials.Australian endodontic journal : the journal of the Australian Society of Endodontology Inc · 2026Article
- LncRNA SLC7A11-AS1 is involved in human periodontal stem cell injury by negatively regulating miR-1260 expression.Odontology · 2026Article
- Biocompatibility, bioactivity and immunomodulatory properties of three calcium silicate-based sealers: an in vitro study on hPDLSCs.Clinical oral investigations · 2024Article
- Keratin as an effective coating material forHeliyon · 2024Article
- Comparative bioactivity and immunomodulatory potential of the new Bioroot Flow and AH Plus Bioceramic sealer: An in vitro study on hPDLSCs.Clinical oral investigations · 2024Article
- Cytotoxicity, Differentiation, and Biocompatibility of Root-End Filling: A Comprehensive Study.Biomimetics (Basel, Switzerland) · 2023Article
- The Contribution of Various In Vitro Methodologies to Comprehending the Filling Ability of Root Canal Pastes in Primary Teeth.Bioengineering (Basel, Switzerland) · 2023Article
Corrections and comments
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Authors and funding
9 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesTo assess the cytocompatibility and bioactive potential of the new calcium silicate-based cement Ceraputty on human periodontal ligament stem cells (hPDLSCs) compared to Biodentine and Endosequence BC root repair material (ERRM). MATERIALS AND
methodshPDLSCs were isolated from extracted third molars from healthy donors. Standardized sample discs and 1:1, 1:2, and 1:4 eluates of the tested materials were prepared. The following assays were performed: surface element distribution via SEM-EDX, cell attachment and morphology via SEM, cell viability via a MTT assay, osteo/cemento/odontogenic marker expression via RT-qPCR, and cell calcified nodule formation via Alizarin Red S staining. hPDLSCs cultured in unconditioned or osteogenic media were used as negative and positive control groups, respectively. Statistical analysis was performed using one-way ANOVA or two-way ANOVA and Tukey's post hoc test. Statistical significance was established at p < 0.05.
resultsThe highest Ca
conclusionCeraputty evidenced a reduced cytocompatibility towards hPDLSCs on its lowest dilutions compared to the other tested cements and the control group. Biodentine and ERRM promoted a significantly higher mineralization and osteo/cementogenic marker expression on hPDLSCs compared with Ceraputty. Further studies are necessary to verify the biological properties of this new material and its adequacy as a retrograde filling material. CLINICAL RELEVANCE: This is the first study to elucidate the adequate biological properties of Ceraputty for its use as a retrograde filling material.
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