Evidence map›Paper›PMID 37125410›Full record

ArticleBiomedical signal processing and control2023

Opportune warning of COVID-19 in a Mexican health care worker cohort: Discrete beta distribution entropy of smartwatch physiological records.

Alejandro Aguado-García, América Arroyo-Valerio, Galileo Escobedo, Nallely Bueno-Hernández, P V Olguín-Rodríguez, Markus F Müller, José Damián Carrillo-Ruiz, Gustavo Martínez-Mekler

Abstract read
In one paragraph

Article in Biomedical signal processing and control, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Alejandro Aguado-GarcíaDirección de Investigación, Hospital General de México, Ciudad de México 06720, Mexico.
América Arroyo-ValerioDirección de Investigación, Hospital General de México, Ciudad de México 06720, Mexico.
Galileo EscobedoDirección de Investigación, Hospital General de México, Ciudad de México 06720, Mexico.
Nallely Bueno-HernándezDirección de Investigación, Hospital General de México, Ciudad de México 06720, Mexico.
P V Olguín-RodríguezInstituto de Ciencias Nucleares, Universidad Nacional Autónoma de México, Ciudad de México, Mexico.
Markus F MüllerCentro de Investigación en Ciencias, Universidad Autónoma del Estado de Morelos, Cuernavaca 62209, Mexico.
José Damián Carrillo-RuizDirección de Investigación, Hospital General de México, Ciudad de México 06720, Mexico.
Gustavo Martínez-MeklerInstituto de Ciencias Físicas, Universidad Nacional Autónoma de México, Cuernavaca 62210, Mexico.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We present a statistical study of heart rate, step cadence, and sleep stage registers of health care workers in the Hospital General de México "Dr. Eduardo Liceaga" (HGM), monitored continuously and non-invasively during the COVID-19 contingency from May to October 2020, using the Fitbit Charge 3® Smartwatch device. The HGM-COVID cohort consisted of 115 participants assigned to areas of COVID-19 exposure. We introduce a novel biomarker for an opportune signal for the likelihood of SARS-CoV-2 infection based on the Shannon Entropy of the Discrete Generalized Beta Distribution fit of rank ordered smartwatch registers. Our statistical test indicated infection for 94% of patients confirmed by positive polymer chain reaction (PCR+) test, 47% before the test, and 47% in coincidence. These results required innovative data preprocessing for the definition of a new biomarker index. The statistical method parameters are data-driven, confidence estimates were calibrated based on sensitivity tests using appropriately derived surrogate data as a benchmark. Our surrogate tests can also provide a benchmark for comparing results from other anomaly detection methods (ADMs). Biomarker comparison of the negative Immunoglobulin G Antibody (IgG-) subgroup with the PCR+ subgroup showed a statistically significant difference (

Indexed as

Biomedical signal processingEarly warningHeart ratePhysiological signalsShannon entropySleep fragmentationTime series analysis

Identifiers

PMID37125410
PMCPMC10121132

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.