ArticleTransplant international : official journal of the European Society for Organ Transplantation2023
Understanding Health-Related Quality of Life in Kidney Transplant Recipients: The Role of Symptom Experience and Illness Perceptions.
Article in Transplant international : official journal of the European Society for Organ Transplantation, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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Who cites it
10 citing papers in PubMed, 14 citations in OpenAlex.
- Patient-reported Outcome Measures in Solid Organ Transplant Recipients: Current use, Challenges, and Recommendations for Future use.Transplantation · 2026Review
- Illness perception and psychosocial adjustment in young and middle-aged liver transplant recipients during the early postoperative period: the serial mediating roles of perceived social support and quality of life.Frontiers in psychology · 2026Article
- Symptom Burden and Patient-Reported Outcomes in Kidney Transplant Recipients: Results From the TransplantLines Biobank and Cohort Studies.Kidney medicine · 2026Article
- Fatigue across different chronic kidney disease populations: experiences and needs of patients.Clinical kidney journal · 2025Article
- Insights Into Health-Related Quality of Life of Kidney Transplant Recipients: A Narrative Review of Associated Factors.Kidney medicine · 2025Review
- [A rapid review: quality of life in adult allogeneic kidney transplantation in the last five years : What can we learn?]Urologie (Heidelberg, Germany) · 2025Review
- Exploring Early Symptom Experiences and Self-Management Strategies Among Postoperative Kidney Transplant Patients on Symptom Management Theory: A Qualitative Study.Patient preference and adherence · 2025Article
- Kidney Transplantation Improves Health-Related Quality of Life in Older Recipients.Transplant international : official journal of the European Society for Organ Transplantation · 2024Article
- Self-Management of Kidney Transplant Recipients Research: A Comprehensive Bibliometric Analysis.Journal of multidisciplinary healthcare · 2024Review
- The Heterogeneity of Symptom Burden and Fear of Progression Among Kidney Transplant Recipients: A Latent Class Analysis.Psychology research and behavior management · 2024Article
Corrections and comments
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Authors and funding
6 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The purpose of our article is to investigate the impact of symptom experience on health related quality of life (HRQOL) in kidney transplant recipients (KTRs) and whether illness perceptions mediated this impact. Symptom experience, illness perceptions, and HRQOL were measured at transplantation and 6 weeks after transplantation in KTRs in an ongoing Dutch cohort study. Multivariable linear regression models were used for the analysis. 90 KTRs were analyzed. Fatigue and lack of energy were the most prevalent and burdensome symptoms at transplantation. Mental HRQOL at 6 weeks after transplantation was comparable to that of the general Dutch population (mean [standard deviation, SD]: 49.9 [10.7]) versus 50.2 [9.2]), while physical HRQOL was significantly lower (38.9 [9.1] versus 50.6 [9.2]). Experiencing more symptoms was associated with lower physical and mental HRQOL, and the corresponding HRQOL reduced by -0.15 (95%CI, -0.31; 0.02) and -0.23 (95%CI, -0.42; -0.04) with each additional symptom. The identified mediation effect suggests that worse symptom experiences could cause more unhelpful illness perceptions and consequently lead to lower HRQOL. Illness perceptions may explain the negative impact of symptom experience on HRQOL. Future studies at later stages after kidney transplantation are needed to further explore the mediation effect of illness perceptions and guide clinical practice to improve HRQOL.
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