Evidence map›Paper›PMID 37125312›Full record

ArticleEuropean heart journal supplements : journal of the European Society of Cardiology2023

Pacing of the specialized His-Purkinje conduction system: 'back to the future'.

Edoardo Bressi, Domenico Grieco, Karol Čurila, Francesco Zanon, Lina Marcantoni, Jose Angel Cabrera, Ermenegildo De Ruvo, Kevin Vernooy, Leonardo Calò

Open access · hybridAbstract read
In one paragraph

Article in European heart journal supplements : journal of the European Society of Cardiology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
0.9field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it, 4 citations in OpenAlex.

  1. Outcomes of Left Bundle Branch Area Pacing in Heart Failure Patients: A Systematic Review.Annals of noninvasive electrocardiology : the official journal of the International Society for Holter and Noninvasive Electrocardiology, Inc · 2026
    Pooled it
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 5 institutions in 4 countries.

Edoardo BressiDepartment of Cardiovascular Sciences, Policlinico Casilino of Rome, Via Casilina, 1049, 00169 Rome, Italy.
Domenico GriecoDepartment of Cardiovascular Sciences, Policlinico Casilino of Rome, Via Casilina, 1049, 00169 Rome, Italy.
Karol ČurilaDepartment of Cardiology, Cardiocenter, Third Faculty of Medicine, Charles University, University Hospital Kralovske Vinohrady, Ruská 2411, 100 00 Prague 10-Vinohrady, Czech Republic.
Francesco ZanonArrhythmia and Electrophysiology Unit, Department of Cardiology, Santa Maria della Misericordia General Hospital, Viale Tre Martiri, 140, 45100 Rovigo, Italy.
Lina MarcantoniArrhythmia and Electrophysiology Unit, Department of Cardiology, Santa Maria della Misericordia General Hospital, Viale Tre Martiri, 140, 45100 Rovigo, Italy.
Jose Angel CabreraUnidad de Arritmias, Departamento de Cardiología, Hospital Universitario Quirón-Salud Madrid and Complejo Hospitalario Ruber Juan Bravo, Universidad Europea de Madrid, Calle de Juan Bravo, 49, 28006 Madrid, Spain.
Ermenegildo De RuvoDepartment of Cardiovascular Sciences, Policlinico Casilino of Rome, Via Casilina, 1049, 00169 Rome, Italy.
Kevin VernooyDepartment of Cardiology, Cardiovascular Research Institute Maastricht (CARIM), Maastricht University Medical Center, P. Debyelaan 25, 6229 HX Maastricht, The Netherlands.
Leonardo CalòDepartment of Cardiovascular Sciences, Policlinico Casilino of Rome, Via Casilina, 1049, 00169 Rome, Italy.
Policlinico Casilino · ITMaastricht University · NLOspedale Santa Maria della Misericordia di Rovigo · ITUniversidad Europea · ESUniversity Hospital Kralovske Vinohrady · CZ

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The conduction system of the human heart is composed of specialized cardiomyocytes that initiate and propagate the electric impulse with consequent rhythmic and synchronized contraction of the atria and ventricles, resulting in the normal cardiac cycle. Although the His-Purkinje system (HPS) was already described more than a century ago, there has been a recent resurgence of conduction system pacing (CSP), where pacing leads are positioned in the His bundle region and left bundle branch area to provide physiological cardiac activation as alternatives to the unnatural myocardial stimulation obtained with conventional right ventricular and biventricular pacing. In this review, we describe the fundamental anatomical and pathophysiological aspects of the specialized HPS along with the CSP technique's nuts and bolts to highlight its potential benefits in everyday clinical practice.

Indexed as

Conduction system pacingHis-bundle pacingHis–Purkinje systemLeft bundle branch area pacingUltra-high-frequency electrocardiogram

Identifiers

PMID37125312
PMCPMC10132574
OpenAlexW4367060227

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.