Evidence map›Paper›PMID 37125257›Full record

ArticleHemaSphere2023

Risk Factors of Progression in Low-tumor Burden Follicular Lymphoma Initially Managed by Watch and Wait in the Era of PET and Rituximab.

Cyrielle Rodier, Lukshe Kanagaratnam, David Morland, Adélie Herbin, Amandine Durand, Adrien Chauchet, Sylvain Choquet, Philippe Colin, René Olivier Casasnovas, Eric Deconinck and 4 more

Open access · goldAbstract read
In one paragraph

Article in HemaSphere, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 3 pooled it
3.3field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 3 syntheses or guidelines pooled it, 13 citations in OpenAlex.

  1. Guideline
  2. Pooled it
  3. Pooled it
  4. Trial
  5. Article
  6. Article
  7. Article
  8. The Predictive Role of BaselineDiagnostics (Basel, Switzerland) · 2025
    Article
  9. Baseline [BMC cancer · 2025
    Article
  10. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 8 institutions in 1 country.

Cyrielle RodierDepartment of Hematology, University Hospital of Reims, Hôpital Robert Debré, Reims, France.
Lukshe KanagaratnamDepartment of Research and Innovation, University Hospital of Reims, Hôpital Robert Debré, Reims, France.
David MorlandMédecine Nucléaire, Institut Godinot, Laboratoire de Biophysique, UFR de Médecine, Université de Reims Champagne-Ardenne, and CReSTIC (Centre de Recherche en Sciences et Technologies de l'Information et de la Communication), EA 3804, Université de Reims Champagne-Ardenne, Reims, France.
Adélie HerbinDepartment of Hematology, University Hospital F. Mitterrand and Inserm UMR 1231, Dijon, France.
Amandine DurandDepartment of Hematology, University Hospital F. Mitterrand and Inserm UMR 1231, Dijon, France.
Adrien ChauchetDepartment of Hematology, University Hospital of Besançon, France.
Sylvain ChoquetDepartment of Hematology, APHP, Groupe Hospitalier Pitié-Salpêtrière, Paris, France.
Philippe ColinDepartment of Oncology, Clinique Courlancy, Reims, France.
René Olivier CasasnovasDepartment of Hematology, University Hospital F. Mitterrand and Inserm UMR 1231, Dijon, France.
Eric DeconinckDepartment of Hematology, University Hospital of Besançon, France.
François GodardMédecine Nucléaire, Centre Georges-François Leclerc, Dijon, France.
Alain DelmerDepartment of Hematology, University Hospital of Reims, Hôpital Robert Debré, Reims, France.
Cédric RossiDepartment of Hematology, University Hospital F. Mitterrand and Inserm UMR 1231, Dijon, France.
Eric DurotDepartment of Hematology, University Hospital of Reims, Hôpital Robert Debré, Reims, France.
Inserm · FRCentre Hospitalier Universitaire de Besançon · FRCentre Hospitalier Universitaire de Reims · FRHôpital Robert-Debré · FRCentre de Recherche en Sciences et Technologies de l'Information et de la Communication · FRCentre Georges François Leclerc · FRL’Institut du Cancer Courlancy Reims · FRPitié-Salpêtrière Hospital · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Patients (pts) with asymptomatic low-burden follicular lymphoma (FL) are usually observed at diagnosis. Time to lymphoma treatment (TLT) initiation can however be very heterogeneous and risk factors of progression are poorly studied. Our study evaluated 201 pts with grade 1-3a low-tumor burden FL diagnosed in four French centers between 2010 and 2020 and managed by a watch and wait strategy in real-life settings. After a median follow-up of 4.8 years, the median TLT was 4.2 years (95% confidence interval, 3.1-5.5). On multivariate analysis, elevated lactate dehydrogenase (hazard ratio [HR] = 2.2;

Identifiers

PMID37125257
PMCPMC10146112
OpenAlexW4367049730

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.