Evidence map›Paper›PMID 37125234›Full record

ArticleOpen forum infectious diseases2023

Perspectives on Diagnosis and Management of All-Cause Encephalitis: A National Survey of Adult Infectious Diseases Physicians.

Marion Le Maréchal, Luisa A Diaz-Arias, Susan E Beekmann, Philip Polgreen, Kevin Messacar, Allan R Tunkel, Kiran T Thakur, Arun Venkatesan

Open access · goldAbstract read
In one paragraph

Article in Open forum infectious diseases, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.4field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 5 institutions in 1 country.

Marion Le MaréchalEncephalitis Center, Johns Hopkins Hospital, Baltimore, Maryland, USA.ORCID https://orcid.org/0000-0002-0063-325X
Luisa A Diaz-AriasEncephalitis Center, Johns Hopkins Hospital, Baltimore, Maryland, USA.
Susan E BeekmannDepartment of Internal Medicine, Carver College of Medicine, University of Iowa, Iowa City, Iowa, USA.
Philip PolgreenDepartment of Epidemiology, College of Public Health, University of Iowa, Iowa City, Iowa, USA.
Kevin MessacarDepartment of Pediatric Infectious Diseases, Children's Hospital Colorado, Aurora, Colorado, USA.
Allan R TunkelWarren Alpert Medical School, Brown University, Providence, Rhode Island, USA.
Kiran T ThakurDepartment of Neurology, Columbia University Irving Medical Center, New York, New York, USA.
Arun VenkatesanEncephalitis Center, Johns Hopkins Hospital, Baltimore, Maryland, USA.
Johns Hopkins Hospital · USUniversity of Iowa · USBrown University · USChildren's Hospital Colorado · USColumbia University Irving Medical Center · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Encephalitis is widely recognized as a challenging condition to diagnose and manage. The care of patients with encephalitis typically involves multiple disciplines, including neurologists and infectious disease (ID) physicians. Our objective was to describe the perspectives and needs of ID physicians regarding encephalitis, using a cross-sectional questionnaire survey. Methods: We performed a survey among physician members of the Infectious Diseases Society of America's (IDSA) Emerging Infections Network (EIN). Results: Response rate was 33% (480 among 1472 active EIN physician members). More than 75% of respondents reported caring for patients with suspected encephalitis. Although one-third were involved in the care of multiple patients with autoimmune encephalitis (AE) annually, comfort in diagnosing and managing encephalitis, and in particular AE, was low. Experience with advanced diagnostic tools was variable, as were approaches toward deployment of such tools. Respondents noted that training could be improved by incorporating a multidisciplinary approach taking advantage of online and virtual platforms. ID physicians report a heavy reliance on the 2008 IDSA guidelines for the management of encephalitis, and indicated strong support for a formal update. Conclusions: ID physicians play an important role in the diagnosis and management of all-cause encephalitis. Despite exposure to AE, few ID physicians are comfortable in recognizing, diagnosing, and treating AE. Moreover, comfort with and use of advanced diagnostic tools for infectious encephalitis was highly variable. Training in encephalitis should include a focus on use and stewardship of advanced diagnostic tools and on collaborative approaches with neurologists and other practitioners on mechanisms and clinical presentations of AE. There is a need for a formal update of 2008 guidelines on the management of encephalitis.

Indexed as

encephalitisguidelinesNGStraining

Identifiers

PMID37125234
PMCPMC10135423
OpenAlexW4327984899

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.