Evidence map›Paper›PMID 37125233›Full record

ArticleOpen forum infectious diseases2023

CMV Infection After Letermovir Primary Prophylaxis Discontinuation in Allogeneic Hematopoietic Cell Transplant Recipients.

Lara Chavaz, Léna Royston, Stavroula Masouridi-Levrat, Anne-Claire Mamez, Federica Giannotti, Sarah Morin, Christian Van Delden, Yves Chalandon, Dionysios Neofytos

Open access · goldAbstract read
In one paragraph

Article in Open forum infectious diseases, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
4.7field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 22 citations in OpenAlex.

  1. Cytomegalovirus Vaccines in Transplantation: History, Hurdles, and Hope.Transplant infectious disease : an official journal of the Transplantation Society · 2026
    Review
  2. Article
  3. Does early letermovir initiation delay engraftment?Antimicrobial agents and chemotherapy · 2026
    Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Review
  9. Observational
  10. Article
  11. Review
  12. Review
  13. Article
  14. Revisiting Cytomegalovirus Serology in Allogeneic Hematopoietic Cell Transplant Recipients.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2024
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Lara ChavazDivision of Infectious Diseases, University Hospital of Geneva, Geneva, Switzerland.ORCID https://orcid.org/0000-0002-8253-465X
Léna RoystonDivision of Infectious Diseases, University Hospital of Geneva, Geneva, Switzerland.
Stavroula Masouridi-LevratDivision of Hematology, Bone Marrow Transplant Unit, University Hospital of Geneva and faculty of Medicine, University of Geneva, Geneva, Switzerland.
Anne-Claire MamezDivision of Hematology, Bone Marrow Transplant Unit, University Hospital of Geneva and faculty of Medicine, University of Geneva, Geneva, Switzerland.
Federica GiannottiDivision of Hematology, Bone Marrow Transplant Unit, University Hospital of Geneva and faculty of Medicine, University of Geneva, Geneva, Switzerland.
Sarah MorinDivision of Hematology, Bone Marrow Transplant Unit, University Hospital of Geneva and faculty of Medicine, University of Geneva, Geneva, Switzerland.
Christian Van DeldenDivision of Infectious Diseases, University Hospital of Geneva, Geneva, Switzerland.
Yves ChalandonDivision of Hematology, Bone Marrow Transplant Unit, University Hospital of Geneva and faculty of Medicine, University of Geneva, Geneva, Switzerland.ORCID https://orcid.org/0000-0001-9341-8104
Dionysios NeofytosDivision of Infectious Diseases, University Hospital of Geneva, Geneva, Switzerland.ORCID https://orcid.org/0000-0001-6970-2869
University of Geneva · CHUniversity Hospital of Geneva · CH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In this single-center study of 61 allogeneic hematopoietic cell transplant (HCT) recipients receiving letermovir primary cytomegalovirus (CMV) prophylaxis for the first 100 days, we report 23% incidence of clinically significant CMV infection during the first 100 days after letermovir discontinuation, predominately in haploidentical HCT recipients, without any associations with CMV-DNAemia under letermovir.

Indexed as

allogeneic hematopoietic cell transplant recipients (allo-HCTr)breakthrough infectioncytomegalovirus (CMV)letermovirprophylaxisrisk factors

Identifiers

PMID37125233
PMCPMC10147386
OpenAlexW4361004274

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.