ArticleFrontiers in nutrition2023
Impact of early enteral nutrition on ventilator associated pneumonia in intubated severe trauma patients: A propensity score-matched study.
Article in Frontiers in nutrition, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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Who cites it
9 citing papers in PubMed, 7 citations in OpenAlex.
- Article
- Effect of Duration of Pre-Procedure Fasting on Clinical Outcomes in Intensive Care Patients Undergoing Percutaneous Tracheostomy.Medical science monitor : international medical journal of experimental and clinical research · 2026Observational
- A potential bundle for preventing ventilator-associated pneumonia in the emergency department: A narrative review.The Journal of international medical research · 2026Article
- Advancements in research on feeding intolerance to enteral nutrition in neurocritical patients undergoing sedation and analgesia.Frontiers in nutrition · 2026Review
- Impact of early enteral nutrition on the prognosis of mechanically ventilated patients with chronic obstructive pulmonary disease: a retrospective cohort study based on the MIMIC-IV Database.Frontiers in nutrition · 2025Article
- Construction and Validation of a Risk Prediction Model for Ventilator-Associated Pneumonia in Mechanically Ventilated Pediatric Patients.Journal of nursing management · 2025Article
- Exploring Global Research Trends in Enteral Nutrition for Mechanically Ventilated Patients: A Comprehensive Bibliometric Study.Journal of multidisciplinary healthcare · 2025Review
- Specialized nursing intervention on critically ill patient in the prevention of intubation-associated pneumonia: an integrative literature review.Acute and critical care · 2024Article
- Early versus delayed enteral nutrition in ICU patients with sepsis: a propensity score-matched analysis based on the MIMIC-IV database.Frontiers in nutrition · 2024Article
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Authors and funding
11 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Early enteral nutrition (EN) is recommended for critically ill patients. However, the impact of early EN on intubated severe trauma patients remains unclear. Methods: Severely traumatized adult patients who received invasive mechanical ventilation (MV) for more than 48 h during intensive care unit (ICU) stay at our institution between 2017 and 2022 were retrospectively included. Early EN was defined as EN initiation ≤48 h from ICU admission and late EN >48 h. Propensity score matching (PSM) analysis was used to compare outcomes between the groups. The primary endpoint was the incidence of ventilator-associated pneumonia (VAP). Multivariable logistic regression analysis was performed to identify independent predictors of delayed EN. Results: For final analysis, 337 intubated severe trauma patients were available, including 204 (60.5%) in the early EN group and 133 (39.5%) in the late EN group. After PSM, early EN patients had a lower incidence of VAP (12.9 vs. 25.8%, Conclusion: Early EN decreased the VAP rate and reduced the length of hospital stay in invasively ventilated patients with severe trauma. Abdominal injury, massive blood transfusion and low albumin were associated with delayed EN.
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