ArticleFrontiers in nutrition2023
Single and combined associations of blood lead and essential metals with serum lipid profiles in community-dwelling adults.
Article in Frontiers in nutrition, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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Who cites it
9 citing papers in PubMed, 15 citations in OpenAlex.
- Exposure to heavy metals and trace elements and risk of dyslipidemia: a nested case-control analysis in rural adults.Frontiers in endocrinology · 2026Article
- Associations of Dietary Magnesium Intake with All-Cause and Cause-Specific Mortality Among Individuals with Gout and Hyperuricemia.Biological trace element research · 2025Article
- Exposure to polycyclic aromatic hydrocarbons, heavy metals, and per- and polyfluoroalkyl substances and their associations with serum lipid profiles in the general Korean adult population.Environmental health : a global access science source · 2025Article
- Associations of per- and polyfluoroalkyl substances and heavy metals with blood lipid profiles in a representative sample of Korean adolescents.Environmental health : a global access science source · 2024Article
- Sex- and age-specific associations of serum essential elements with diabetes among the Chinese adults: a community-based cross-sectional study.Nutrition & metabolism · 2024Article
- Article
- Association between blood lead, cadmium, selenium levels and hyperlipidemia: A population-based study.PloS one · 2024Article
- Comparative mathematical modeling of causal association between metal exposure and development of chronic kidney disease.Frontiers in endocrinology · 2024Article
- Article
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Authors and funding
13 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Although several studies have examined the relationships between lead (Pb) exposure and serum lipid profiles, the associations of the metal mixture, including lead (Pb) and essential metals with lipid profiles, remain unclear. Objective: To investigate the associations of the metal mixture including Pb and essential metals [magnesium (Mg), manganese (Mn), copper (Cu), iron (Fe), zinc (Zn), and calcium (Ca)] with serum lipid profiles [total cholesterol (TC), triglyceride (TG), low-density lipoprotein cholesterol (LDL-C), and high-density lipoprotein cholesterol (HDL-C)], as well as the potential interactions among the metals. Methods: Nine hundred and ninety-eight Chinese community-dwelling adults completed a questionnaire and underwent checkups of anthropometric parameters, serum lipid profile levels (TC, TG, LDL-C, and HDL-C), and blood metal concentrations (Pb, Mg, Mn, Cu, Fe, Zn, and Ca). The multivariable linear regression, weighted quantile sum (WQS) regression, and Bayesian kernel machine regression (BKMR) were applied to evaluate the single and combined associations of blood Pb and essential metals with serum lipid profiles. Results: In the multivariable linear regression model, the blood Pb was positively associated with TC, LDL-C, and HDL-C ( Conclusion: The levels of blood Pb, together with the essential metals, especially Mg levels, are suggested to be considered when assessing dyslipidemia risk. However, more evidence is still needed to validate the conclusions.
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