Evidence map›Paper›PMID 37124745›Full record

ArticleFrontiers in endocrinology2023

Analysis of sperm chromatin packaging and reproductive biomarker to evaluate the consequence of advanced male age.

Riffat Bibi, Sarwat Jahan, Salma Kafeel Qureshi, Suhail Razak, Tayyaba Afsar, Ali Almajwal, Mashal Kafeel Qureshi, Mohammad Eid Hammadeh, Houda Amor

Abstract read
In one paragraph

Article in Frontiers in endocrinology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Review
  3. Sperm chromatin structure assay (SCSABasic and clinical andrology · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Riffat BibiDepartment of Animal Sciences, Faculty of Biological Sciences, Quaid-i-Azam University Islamabad, Islamabad, Pakistan.
Sarwat JahanDepartment of Animal Sciences, Faculty of Biological Sciences, Quaid-i-Azam University Islamabad, Islamabad, Pakistan.
Salma Kafeel QureshiDepartment of Reproductive Health Sciences, Salma and Kafeel Medical Centre, Islamabad, Pakistan.
Suhail RazakDepartment of Community Health Sciences, College of Applied Medical Sciences, King Saud University, Riyadh, Saudi Arabia.
Tayyaba AfsarDepartment of Community Health Sciences, College of Applied Medical Sciences, King Saud University, Riyadh, Saudi Arabia.
Ali AlmajwalDepartment of Community Health Sciences, College of Applied Medical Sciences, King Saud University, Riyadh, Saudi Arabia.
Mashal Kafeel QureshiDepartment of Reproductive Health Sciences, Salma and Kafeel Medical Centre, Islamabad, Pakistan.
Mohammad Eid HammadehDepartment of Obstetrics, Gynecology and Reproductive Medicine, Saarland University Clinic, Homburg, Germany.
Houda AmorDepartment of Obstetrics, Gynecology and Reproductive Medicine, Saarland University Clinic, Homburg, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In this study, the semen parameters, sperm chromatin integrity, antioxidant enzyme levels, and reproductive hormone levels of subfertile male subjects from Pakistan were assessed in relation to their age. Data on the demographic characteristics of the 750 study participants, including their general health, body mass index (BMI), and reproductive status, were collected from subfertile men from Pakistan. Semen and blood were collected to determine standard semen parameters, sperm chromatin dispersion (Halosperm-SCD), sperm chromatin integrity using toluidine blue (TB) staining, sperm chromatin maturity using chromomycin A3 (CMA3+) staining, and reproductive hormone (FSH, LH, prolactin and testosterone levels). The patients were divided into three groups according to their age: Group 1 included male subjects aged 30 years or less (

Indexed as

Infertility, MaleSemenBiomarkersChromatinFollicle Stimulating HormoneHumansMaleProlactinSpermatozoaSperm CountSperm MotilityTestosteroneBiomarkersChromatinFollicle Stimulating HormoneProlactinTestosteroneassisted reproductive proceduresmale agereproductive markersperm chromatin integritysperm deoxyribose nucleic acid fragmentation index

Identifiers

PMID37124745
PMCPMC10140363

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.