ArticleRadiology. Cardiothoracic imaging2023
MRI Compared with Low-Dose CT for Incidental Lung Nodule Detection in COPD: A Multicenter Trial.
2 registry-linked trialsOpen access · greenAbstract read
In one paragraph
Article in Radiology. Cardiothoracic imaging, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 8 papers, 1 of them a synthesis that pooled it.
0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
3.6field-weighted citation impact, top 7% of its field
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Impact of Systemic Manifestations/Comorbidities on Clinical State, Prognosis and Utilisation of Health Care Resources in Patients With COPD
Image-Based Structural and Functional Phenotyping of the COSYCONET Cohort Using MRI and CT (MR COPD)
Who cites it
8 citing papers in PubMed, 1 synthesis or guideline pooled it, 14 citations in OpenAlex.
- Diagnostic Performance of MRI for the Detection of Pulmonary Nodules: A Systematic Review and Meta-Analysis.Radiology. Cardiothoracic imaging · 2024Pooled it
- MRI for Lung Cancer Management: Any Closer to Clinical Application?Journal of magnetic resonance imaging : JMRI · 2026Review
- A multiparameter diagnostic model based on MRI volumetric ADC histogram and clinical variables accurately differentiates thymic epithelial tumors from mediastinal lymphomas.BMC medical imaging · 2026Article
- Longitudinal MRI in comparison to low-dose CT for follow-up of incidental pulmonary nodules in patients with COPD-a nationwide multicenter trial.European radiology · 2025Article
- GOLD grade-specific characterization of COPD in the COSYCONET multi-center trial: comparison of semiquantitative MRI and quantitative CT.European radiology · 2025Article
- In situ expansion capacity evaluation of terminal alveoli in chronic obstructive pulmonary disease using an ultrathin optical coherence tomography catheter.Biomedical optics express · 2025Article
- Assessments of lung nodules by an artificial intelligence chatbot using longitudinal CT images.Cell reports. Medicine · 2025Article
- Phenotyping of COPD with MRI in comparison to same-day CT in a multi-centre trial.European radiology · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
14 authors at 18 institutions in 2 countries.
Qian Li *Department of Diagnostic and Interventional Radiology, University Hospital of Heidelberg, Im Neuenheimer Feld 420, 69120 Heidelberg, Germany (Q.L., L.Z., O.v.S., S.M.F.T., J.B., O.W., M.E., H.U.K., C.P.H., B.J.J., M.O.W.); Translational Lung Research Center Heidelberg (TLRC), German Center for Lung Research (DZL), Heidelberg, Germany (Q.L., L.Z., O.v.S., S.M.F.T., J.B., O.W., M.E., H.U.K., C.P.H., B.J.J., M.O.W.); Department of Diagnostic and Interventional Radiology with Nuclear Medicine, Thoraxklinik at the University Hospital of Heidelberg, Heidelberg, Germany (Q.L., L.Z., O.v.S., S.M.F.T., O.W., M.E., H.U.K., C.P.H., B.J.J., M.O.W.); Department of Radiology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China (Q.L.); Department of Radiology, Shanghai Chest Hospital, Shanghai Jiao Tong University, Shanghai, China (L.Z.); University of Latvia, Faculty of Medicine, Riga, Latvia (J.B.); Christian-Albrechts-Universität zu Kiel, Faculty of Medicine, Kiel, Germany (J.B.); Department of Medicine, Pulmonary and Critical Care Medicine, Philipps-University of Marburg (UMR), Marburg, Germany (C.F.V.); and Institute and Outpatient Clinic for Occupational, Social and Environmental Medicine, University Hospital, Ludwig Maximilians University (LMU) Munich, Comprehensive Pneumology Center Munich (CPC-M), Munich, Germany (R.A.J.).ORCID https://orcid.org/0000-0002-9048-762X
Lin Zhu *Department of Diagnostic and Interventional Radiology, University Hospital of Heidelberg, Im Neuenheimer Feld 420, 69120 Heidelberg, Germany (Q.L., L.Z., O.v.S., S.M.F.T., J.B., O.W., M.E., H.U.K., C.P.H., B.J.J., M.O.W.); Translational Lung Research Center Heidelberg (TLRC), German Center for Lung Research (DZL), Heidelberg, Germany (Q.L., L.Z., O.v.S., S.M.F.T., J.B., O.W., M.E., H.U.K., C.P.H., B.J.J., M.O.W.); Department of Diagnostic and Interventional Radiology with Nuclear Medicine, Thoraxklinik at the University Hospital of Heidelberg, Heidelberg, Germany (Q.L., L.Z., O.v.S., S.M.F.T., O.W., M.E., H.U.K., C.P.H., B.J.J., M.O.W.); Department of Radiology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China (Q.L.); Department of Radiology, Shanghai Chest Hospital, Shanghai Jiao Tong University, Shanghai, China (L.Z.); University of Latvia, Faculty of Medicine, Riga, Latvia (J.B.); Christian-Albrechts-Universität zu Kiel, Faculty of Medicine, Kiel, Germany (J.B.); Department of Medicine, Pulmonary and Critical Care Medicine, Philipps-University of Marburg (UMR), Marburg, Germany (C.F.V.); and Institute and Outpatient Clinic for Occupational, Social and Environmental Medicine, University Hospital, Ludwig Maximilians University (LMU) Munich, Comprehensive Pneumology Center Munich (CPC-M), Munich, Germany (R.A.J.).ORCID 0000-0003-0322-9321
Oyunbileg von StackelbergDepartment of Diagnostic and Interventional Radiology, University Hospital of Heidelberg, Im Neuenheimer Feld 420, 69120 Heidelberg, Germany (Q.L., L.Z., O.v.S., S.M.F.T., J.B., O.W., M.E., H.U.K., C.P.H., B.J.J., M.O.W.); Translational Lung Research Center Heidelberg (TLRC), German Center for Lung Research (DZL), Heidelberg, Germany (Q.L., L.Z., O.v.S., S.M.F.T., J.B., O.W., M.E., H.U.K., C.P.H., B.J.J., M.O.W.); Department of Diagnostic and Interventional Radiology with Nuclear Medicine, Thoraxklinik at the University Hospital of Heidelberg, Heidelberg, Germany (Q.L., L.Z., O.v.S., S.M.F.T., O.W., M.E., H.U.K., C.P.H., B.J.J., M.O.W.); Department of Radiology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China (Q.L.); Department of Radiology, Shanghai Chest Hospital, Shanghai Jiao Tong University, Shanghai, China (L.Z.); University of Latvia, Faculty of Medicine, Riga, Latvia (J.B.); Christian-Albrechts-Universität zu Kiel, Faculty of Medicine, Kiel, Germany (J.B.); Department of Medicine, Pulmonary and Critical Care Medicine, Philipps-University of Marburg (UMR), Marburg, Germany (C.F.V.); and Institute and Outpatient Clinic for Occupational, Social and Environmental Medicine, University Hospital, Ludwig Maximilians University (LMU) Munich, Comprehensive Pneumology Center Munich (CPC-M), Munich, Germany (R.A.J.).
Simon M F TriphanDepartment of Diagnostic and Interventional Radiology, University Hospital of Heidelberg, Im Neuenheimer Feld 420, 69120 Heidelberg, Germany (Q.L., L.Z., O.v.S., S.M.F.T., J.B., O.W., M.E., H.U.K., C.P.H., B.J.J., M.O.W.); Translational Lung Research Center Heidelberg (TLRC), German Center for Lung Research (DZL), Heidelberg, Germany (Q.L., L.Z., O.v.S., S.M.F.T., J.B., O.W., M.E., H.U.K., C.P.H., B.J.J., M.O.W.); Department of Diagnostic and Interventional Radiology with Nuclear Medicine, Thoraxklinik at the University Hospital of Heidelberg, Heidelberg, Germany (Q.L., L.Z., O.v.S., S.M.F.T., O.W., M.E., H.U.K., C.P.H., B.J.J., M.O.W.); Department of Radiology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China (Q.L.); Department of Radiology, Shanghai Chest Hospital, Shanghai Jiao Tong University, Shanghai, China (L.Z.); University of Latvia, Faculty of Medicine, Riga, Latvia (J.B.); Christian-Albrechts-Universität zu Kiel, Faculty of Medicine, Kiel, Germany (J.B.); Department of Medicine, Pulmonary and Critical Care Medicine, Philipps-University of Marburg (UMR), Marburg, Germany (C.F.V.); and Institute and Outpatient Clinic for Occupational, Social and Environmental Medicine, University Hospital, Ludwig Maximilians University (LMU) Munich, Comprehensive Pneumology Center Munich (CPC-M), Munich, Germany (R.A.J.).
Jürgen BiedererDepartment of Diagnostic and Interventional Radiology, University Hospital of Heidelberg, Im Neuenheimer Feld 420, 69120 Heidelberg, Germany (Q.L., L.Z., O.v.S., S.M.F.T., J.B., O.W., M.E., H.U.K., C.P.H., B.J.J., M.O.W.); Translational Lung Research Center Heidelberg (TLRC), German Center for Lung Research (DZL), Heidelberg, Germany (Q.L., L.Z., O.v.S., S.M.F.T., J.B., O.W., M.E., H.U.K., C.P.H., B.J.J., M.O.W.); Department of Diagnostic and Interventional Radiology with Nuclear Medicine, Thoraxklinik at the University Hospital of Heidelberg, Heidelberg, Germany (Q.L., L.Z., O.v.S., S.M.F.T., O.W., M.E., H.U.K., C.P.H., B.J.J., M.O.W.); Department of Radiology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China (Q.L.); Department of Radiology, Shanghai Chest Hospital, Shanghai Jiao Tong University, Shanghai, China (L.Z.); University of Latvia, Faculty of Medicine, Riga, Latvia (J.B.); Christian-Albrechts-Universität zu Kiel, Faculty of Medicine, Kiel, Germany (J.B.); Department of Medicine, Pulmonary and Critical Care Medicine, Philipps-University of Marburg (UMR), Marburg, Germany (C.F.V.); and Institute and Outpatient Clinic for Occupational, Social and Environmental Medicine, University Hospital, Ludwig Maximilians University (LMU) Munich, Comprehensive Pneumology Center Munich (CPC-M), Munich, Germany (R.A.J.).ORCID 0000-0003-4295-3451
Oliver WeinheimerDepartment of Diagnostic and Interventional Radiology, University Hospital of Heidelberg, Im Neuenheimer Feld 420, 69120 Heidelberg, Germany (Q.L., L.Z., O.v.S., S.M.F.T., J.B., O.W., M.E., H.U.K., C.P.H., B.J.J., M.O.W.); Translational Lung Research Center Heidelberg (TLRC), German Center for Lung Research (DZL), Heidelberg, Germany (Q.L., L.Z., O.v.S., S.M.F.T., J.B., O.W., M.E., H.U.K., C.P.H., B.J.J., M.O.W.); Department of Diagnostic and Interventional Radiology with Nuclear Medicine, Thoraxklinik at the University Hospital of Heidelberg, Heidelberg, Germany (Q.L., L.Z., O.v.S., S.M.F.T., O.W., M.E., H.U.K., C.P.H., B.J.J., M.O.W.); Department of Radiology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China (Q.L.); Department of Radiology, Shanghai Chest Hospital, Shanghai Jiao Tong University, Shanghai, China (L.Z.); University of Latvia, Faculty of Medicine, Riga, Latvia (J.B.); Christian-Albrechts-Universität zu Kiel, Faculty of Medicine, Kiel, Germany (J.B.); Department of Medicine, Pulmonary and Critical Care Medicine, Philipps-University of Marburg (UMR), Marburg, Germany (C.F.V.); and Institute and Outpatient Clinic for Occupational, Social and Environmental Medicine, University Hospital, Ludwig Maximilians University (LMU) Munich, Comprehensive Pneumology Center Munich (CPC-M), Munich, Germany (R.A.J.).
Monika EichingerDepartment of Diagnostic and Interventional Radiology, University Hospital of Heidelberg, Im Neuenheimer Feld 420, 69120 Heidelberg, Germany (Q.L., L.Z., O.v.S., S.M.F.T., J.B., O.W., M.E., H.U.K., C.P.H., B.J.J., M.O.W.); Translational Lung Research Center Heidelberg (TLRC), German Center for Lung Research (DZL), Heidelberg, Germany (Q.L., L.Z., O.v.S., S.M.F.T., J.B., O.W., M.E., H.U.K., C.P.H., B.J.J., M.O.W.); Department of Diagnostic and Interventional Radiology with Nuclear Medicine, Thoraxklinik at the University Hospital of Heidelberg, Heidelberg, Germany (Q.L., L.Z., O.v.S., S.M.F.T., O.W., M.E., H.U.K., C.P.H., B.J.J., M.O.W.); Department of Radiology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China (Q.L.); Department of Radiology, Shanghai Chest Hospital, Shanghai Jiao Tong University, Shanghai, China (L.Z.); University of Latvia, Faculty of Medicine, Riga, Latvia (J.B.); Christian-Albrechts-Universität zu Kiel, Faculty of Medicine, Kiel, Germany (J.B.); Department of Medicine, Pulmonary and Critical Care Medicine, Philipps-University of Marburg (UMR), Marburg, Germany (C.F.V.); and Institute and Outpatient Clinic for Occupational, Social and Environmental Medicine, University Hospital, Ludwig Maximilians University (LMU) Munich, Comprehensive Pneumology Center Munich (CPC-M), Munich, Germany (R.A.J.).
Claus F VogelmeierDepartment of Diagnostic and Interventional Radiology, University Hospital of Heidelberg, Im Neuenheimer Feld 420, 69120 Heidelberg, Germany (Q.L., L.Z., O.v.S., S.M.F.T., J.B., O.W., M.E., H.U.K., C.P.H., B.J.J., M.O.W.); Translational Lung Research Center Heidelberg (TLRC), German Center for Lung Research (DZL), Heidelberg, Germany (Q.L., L.Z., O.v.S., S.M.F.T., J.B., O.W., M.E., H.U.K., C.P.H., B.J.J., M.O.W.); Department of Diagnostic and Interventional Radiology with Nuclear Medicine, Thoraxklinik at the University Hospital of Heidelberg, Heidelberg, Germany (Q.L., L.Z., O.v.S., S.M.F.T., O.W., M.E., H.U.K., C.P.H., B.J.J., M.O.W.); Department of Radiology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China (Q.L.); Department of Radiology, Shanghai Chest Hospital, Shanghai Jiao Tong University, Shanghai, China (L.Z.); University of Latvia, Faculty of Medicine, Riga, Latvia (J.B.); Christian-Albrechts-Universität zu Kiel, Faculty of Medicine, Kiel, Germany (J.B.); Department of Medicine, Pulmonary and Critical Care Medicine, Philipps-University of Marburg (UMR), Marburg, Germany (C.F.V.); and Institute and Outpatient Clinic for Occupational, Social and Environmental Medicine, University Hospital, Ludwig Maximilians University (LMU) Munich, Comprehensive Pneumology Center Munich (CPC-M), Munich, Germany (R.A.J.).ORCID 0000-0002-9798-2527
Rudolf A JörresDepartment of Diagnostic and Interventional Radiology, University Hospital of Heidelberg, Im Neuenheimer Feld 420, 69120 Heidelberg, Germany (Q.L., L.Z., O.v.S., S.M.F.T., J.B., O.W., M.E., H.U.K., C.P.H., B.J.J., M.O.W.); Translational Lung Research Center Heidelberg (TLRC), German Center for Lung Research (DZL), Heidelberg, Germany (Q.L., L.Z., O.v.S., S.M.F.T., J.B., O.W., M.E., H.U.K., C.P.H., B.J.J., M.O.W.); Department of Diagnostic and Interventional Radiology with Nuclear Medicine, Thoraxklinik at the University Hospital of Heidelberg, Heidelberg, Germany (Q.L., L.Z., O.v.S., S.M.F.T., O.W., M.E., H.U.K., C.P.H., B.J.J., M.O.W.); Department of Radiology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China (Q.L.); Department of Radiology, Shanghai Chest Hospital, Shanghai Jiao Tong University, Shanghai, China (L.Z.); University of Latvia, Faculty of Medicine, Riga, Latvia (J.B.); Christian-Albrechts-Universität zu Kiel, Faculty of Medicine, Kiel, Germany (J.B.); Department of Medicine, Pulmonary and Critical Care Medicine, Philipps-University of Marburg (UMR), Marburg, Germany (C.F.V.); and Institute and Outpatient Clinic for Occupational, Social and Environmental Medicine, University Hospital, Ludwig Maximilians University (LMU) Munich, Comprehensive Pneumology Center Munich (CPC-M), Munich, Germany (R.A.J.).ORCID 0000-0002-9782-1117
Hans-Ulrich KauczorDepartment of Diagnostic and Interventional Radiology, University Hospital of Heidelberg, Im Neuenheimer Feld 420, 69120 Heidelberg, Germany (Q.L., L.Z., O.v.S., S.M.F.T., J.B., O.W., M.E., H.U.K., C.P.H., B.J.J., M.O.W.); Translational Lung Research Center Heidelberg (TLRC), German Center for Lung Research (DZL), Heidelberg, Germany (Q.L., L.Z., O.v.S., S.M.F.T., J.B., O.W., M.E., H.U.K., C.P.H., B.J.J., M.O.W.); Department of Diagnostic and Interventional Radiology with Nuclear Medicine, Thoraxklinik at the University Hospital of Heidelberg, Heidelberg, Germany (Q.L., L.Z., O.v.S., S.M.F.T., O.W., M.E., H.U.K., C.P.H., B.J.J., M.O.W.); Department of Radiology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China (Q.L.); Department of Radiology, Shanghai Chest Hospital, Shanghai Jiao Tong University, Shanghai, China (L.Z.); University of Latvia, Faculty of Medicine, Riga, Latvia (J.B.); Christian-Albrechts-Universität zu Kiel, Faculty of Medicine, Kiel, Germany (J.B.); Department of Medicine, Pulmonary and Critical Care Medicine, Philipps-University of Marburg (UMR), Marburg, Germany (C.F.V.); and Institute and Outpatient Clinic for Occupational, Social and Environmental Medicine, University Hospital, Ludwig Maximilians University (LMU) Munich, Comprehensive Pneumology Center Munich (CPC-M), Munich, Germany (R.A.J.).ORCID 0000-0002-6730-9462
Claus P HeußelDepartment of Diagnostic and Interventional Radiology, University Hospital of Heidelberg, Im Neuenheimer Feld 420, 69120 Heidelberg, Germany (Q.L., L.Z., O.v.S., S.M.F.T., J.B., O.W., M.E., H.U.K., C.P.H., B.J.J., M.O.W.); Translational Lung Research Center Heidelberg (TLRC), German Center for Lung Research (DZL), Heidelberg, Germany (Q.L., L.Z., O.v.S., S.M.F.T., J.B., O.W., M.E., H.U.K., C.P.H., B.J.J., M.O.W.); Department of Diagnostic and Interventional Radiology with Nuclear Medicine, Thoraxklinik at the University Hospital of Heidelberg, Heidelberg, Germany (Q.L., L.Z., O.v.S., S.M.F.T., O.W., M.E., H.U.K., C.P.H., B.J.J., M.O.W.); Department of Radiology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China (Q.L.); Department of Radiology, Shanghai Chest Hospital, Shanghai Jiao Tong University, Shanghai, China (L.Z.); University of Latvia, Faculty of Medicine, Riga, Latvia (J.B.); Christian-Albrechts-Universität zu Kiel, Faculty of Medicine, Kiel, Germany (J.B.); Department of Medicine, Pulmonary and Critical Care Medicine, Philipps-University of Marburg (UMR), Marburg, Germany (C.F.V.); and Institute and Outpatient Clinic for Occupational, Social and Environmental Medicine, University Hospital, Ludwig Maximilians University (LMU) Munich, Comprehensive Pneumology Center Munich (CPC-M), Munich, Germany (R.A.J.).
Bertram J JobstDepartment of Diagnostic and Interventional Radiology, University Hospital of Heidelberg, Im Neuenheimer Feld 420, 69120 Heidelberg, Germany (Q.L., L.Z., O.v.S., S.M.F.T., J.B., O.W., M.E., H.U.K., C.P.H., B.J.J., M.O.W.); Translational Lung Research Center Heidelberg (TLRC), German Center for Lung Research (DZL), Heidelberg, Germany (Q.L., L.Z., O.v.S., S.M.F.T., J.B., O.W., M.E., H.U.K., C.P.H., B.J.J., M.O.W.); Department of Diagnostic and Interventional Radiology with Nuclear Medicine, Thoraxklinik at the University Hospital of Heidelberg, Heidelberg, Germany (Q.L., L.Z., O.v.S., S.M.F.T., O.W., M.E., H.U.K., C.P.H., B.J.J., M.O.W.); Department of Radiology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China (Q.L.); Department of Radiology, Shanghai Chest Hospital, Shanghai Jiao Tong University, Shanghai, China (L.Z.); University of Latvia, Faculty of Medicine, Riga, Latvia (J.B.); Christian-Albrechts-Universität zu Kiel, Faculty of Medicine, Kiel, Germany (J.B.); Department of Medicine, Pulmonary and Critical Care Medicine, Philipps-University of Marburg (UMR), Marburg, Germany (C.F.V.); and Institute and Outpatient Clinic for Occupational, Social and Environmental Medicine, University Hospital, Ludwig Maximilians University (LMU) Munich, Comprehensive Pneumology Center Munich (CPC-M), Munich, Germany (R.A.J.).
Mark O WielpützDepartment of Diagnostic and Interventional Radiology, University Hospital of Heidelberg, Im Neuenheimer Feld 420, 69120 Heidelberg, Germany (Q.L., L.Z., O.v.S., S.M.F.T., J.B., O.W., M.E., H.U.K., C.P.H., B.J.J., M.O.W.); Translational Lung Research Center Heidelberg (TLRC), German Center for Lung Research (DZL), Heidelberg, Germany (Q.L., L.Z., O.v.S., S.M.F.T., J.B., O.W., M.E., H.U.K., C.P.H., B.J.J., M.O.W.); Department of Diagnostic and Interventional Radiology with Nuclear Medicine, Thoraxklinik at the University Hospital of Heidelberg, Heidelberg, Germany (Q.L., L.Z., O.v.S., S.M.F.T., O.W., M.E., H.U.K., C.P.H., B.J.J., M.O.W.); Department of Radiology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China (Q.L.); Department of Radiology, Shanghai Chest Hospital, Shanghai Jiao Tong University, Shanghai, China (L.Z.); University of Latvia, Faculty of Medicine, Riga, Latvia (J.B.); Christian-Albrechts-Universität zu Kiel, Faculty of Medicine, Kiel, Germany (J.B.); Department of Medicine, Pulmonary and Critical Care Medicine, Philipps-University of Marburg (UMR), Marburg, Germany (C.F.V.); and Institute and Outpatient Clinic for Occupational, Social and Environmental Medicine, University Hospital, Ludwig Maximilians University (LMU) Munich, Comprehensive Pneumology Center Munich (CPC-M), Munich, Germany (R.A.J.).ORCID 0000-0001-6962-037X
COSYCONET Study Group
Heidelberg University · DEUniversitätsklinikum Gießen und Marburg · DEHautklinik Heidelberg · DEUniversitätsmedizin Greifswald · DEBG University Hospital Bergmannsheil Bochum · DEJustus-Liebig-Universität Gießen · DELungenClinic Grosshansdorf · DENuremberg Hospital · DEResearch Center Borstel - Leibniz Lung Center · DERuhrlandklinik · DEUniversitätsklinikum des Saarlandes · DEUniversity Hospital Schleswig-Holstein · DEAsklepios Fachkliniken München-Gauting · DEKlinikum Würzburg Mitte · DEKrankenhaus Bethanien · DELudwig-Maximilians-Universität München · DEMedizinische Hochschule Hannover · DEUniversity Hospital Leipzig · DE
Funding
No grant is acknowledged in the PubMed record.
Abstract
Purpose: To investigate morphofunctional chest MRI for the detection and management of incidental pulmonary nodules in participants with chronic obstructive pulmonary disease (COPD). Materials and Methods: In this prospective study, 567 participants (mean age, 66 years ± 9 [SD]; 340 men) underwent same-day contrast-enhanced MRI and nonenhanced low-dose CT (LDCT) in a nationwide multicenter trial (clinicaltrials.gov: NCT01245933). Nodule dimensions, morphologic features, and Lung Imaging Reporting and Data System (Lung-RADS) category were assessed at MRI by two blinded radiologists, and consensual LDCT results served as the reference standard. Comparisons were performed using the Student Results: A total of 525 nodules larger than 3 mm in diameter were detected at LDCT in 178 participants, with a mean diameter of 7.2 mm ± 6.1 (range, 3.1-63.1 mm). Nodules were not detected in the remaining 389 participants. Sensitivity and positive predictive values with MRI for readers 1 and 2, respectively, were 63.0% and 84.8% and 60.2% and 83.9% for solid nodules ( Conclusion: In a multicenter setting, morphofunctional MRI showed moderate sensitivity for detection of incidental pulmonary nodules in participants with COPD but high agreement with LDCT for Lung-RADS classification of nodules.Clinical trial registration no. NCT01245933 and NCT02629432
Indexed as
Chronic Obstructive Pulmonary DiseaseCTLungMRIScreeningThorax
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NCT01245933ClinicalTrials.gov
NCT02629432ClinicalTrials.gov
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