Evidence map›Paper›PMID 37124626›Full record

ArticleFrontiers in genetics2023

MicroRNA-21 and microRNA-148a affects PTEN, NO and ROS in canine leishmaniasis.

Jéssica Henrique De Freitas, Jaqueline Poleto Bragato, Gabriela Torres Rebech, Sidnei Ferro Costa, Marilene Oliveira Dos Santos, Matheus Fujimura Soares, Flávia de Rezende Eugênio, Paulo Sérgio Patto Dos Santos, Valéria Marçal Felix De Lima

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in genetics, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.9field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Jéssica Henrique De FreitasDepartment of Animal Clinic, School of Veterinary Medicine, Surgery and Reproduction, São Paulo State University (UNESP), Araçatuba, Brazil.
Jaqueline Poleto BragatoDepartment of Animal Clinic, School of Veterinary Medicine, Surgery and Reproduction, São Paulo State University (UNESP), Araçatuba, Brazil.
Gabriela Torres RebechDepartment of Animal Clinic, School of Veterinary Medicine, Surgery and Reproduction, São Paulo State University (UNESP), Araçatuba, Brazil.
Sidnei Ferro CostaDepartment of Animal Clinic, School of Veterinary Medicine, Surgery and Reproduction, São Paulo State University (UNESP), Araçatuba, Brazil.
Marilene Oliveira Dos SantosDepartment of Animal Clinic, School of Veterinary Medicine, Surgery and Reproduction, São Paulo State University (UNESP), Araçatuba, Brazil.
Matheus Fujimura SoaresDepartment of Animal Clinic, School of Veterinary Medicine, Surgery and Reproduction, São Paulo State University (UNESP), Araçatuba, Brazil.
Flávia de Rezende EugênioDepartment of Animal Clinic, School of Veterinary Medicine, Surgery and Reproduction, São Paulo State University (UNESP), Araçatuba, Brazil.
Paulo Sérgio Patto Dos SantosDepartment of Animal Clinic, School of Veterinary Medicine, Surgery and Reproduction, São Paulo State University (UNESP), Araçatuba, Brazil.
Valéria Marçal Felix De LimaDepartment of Animal Clinic, School of Veterinary Medicine, Surgery and Reproduction, São Paulo State University (UNESP), Araçatuba, Brazil.
Universidade Estadual Paulista (Unesp) · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Canine Visceral leishmaniasis (CanL) poses a severe public health threat in several countries. Disease progression depends on the degree of immune response suppression. MicroRNAs (miRs) modulate mRNA translation into proteins and regulate various cellular functions and pathways associated with immune responses. MiR-21 and miR-148a can alter the parasite load and M1 macrophages are the principal cells in dogs' leishmanicidal activity. A previous study found increased miR-21 and miR-148a in splenic leukocytes (SL) of dogs with CanL using microarray analysis and

Indexed as

Leishmania infantummicroRNAnitriteNOptenROSsplenic leukocytes

Identifiers

PMID37124626
PMCPMC10137164
OpenAlexW4365514671

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.