ArticleFrontiers in oncology2023
Diagnostic value of the apparent diffusion coefficient in differentiating malignant from benign endometrial lesions.
Article in Frontiers in oncology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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Who cites it
5 citing papers in PubMed, 10 citations in OpenAlex.
- Apparent diffusion coefficient values on MRI as biomarkers for pre operative prediction of prognostic factors in endometrial cancer.Gynecologic oncology reports · 2026Article
- Apparent diffusion coefficient values of lymph nodes in endometrial cancer: can they predict lymph node metastases? - a retrospective study.Abdominal radiology (New York) · 2026Observational
- Preoperative risk assessment of endometrial cancer using histogram analysis of weighted and quantitative MRI images.Abdominal radiology (New York) · 2026Article
- Diffusion-Weighted MRI as a Non-Invasive Diagnostic Tool for Ascites Characterization: A Comparative Analysis of Mean and Minimum ADC Values Against the Serum-Ascites Albumin Gradient.Diagnostics (Basel, Switzerland) · 2025Article
- The performance of DWI and ADC values with different b-values for the diagnosis and staging of endometrial carcinoma at 3T.Cancer imaging : the official publication of the International Cancer Imaging Society · 2025Article
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Authors and funding
7 authors at 3 institutions in 1 country.
Funding
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Abstract
Introduction: Magnetic resonance imaging (MRI) with its innovative techniques, such as diffusion-weighted imaging (DWI) and apparent diffusion coefficient (ADC), increases the diagnostic accuracy in distinguishing between malignant and benign lesions of the endometrium. The aim of the study was MRI differentiation between malignant and benign endometrial lesions and correlation with histopathological findings with a special emphasis on quantitative analysis. An additional aim was to correlate the ADC values and histological tumor grades. Methods: The prospective study included 119 female patients with or without vaginal bleeding and pathological values of endometrial thickness, who underwent MRI examinations. According to MRI reports the patients were divided into 45 suspicious malignant and 74 suspicious benign endometrial lesions. The radiological diagnosis was compared to the histopathological evaluation, which confirmed 37 malignant lesions while the rest were benign. Results: The mean ADC value for malignant lesions was 0.761 ± 0.13×10 Conclusion: DWI and ADC values represent clinically useful tools for the differentiation between malignant and benign endometrial lesions with high sensitivity and good specificity, but the results failed to demonstrate their usefulness in differentiating histological grades of endometrial cancer.
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