Evidence map›Paper›PMID 37124510›Full record

ArticleFrontiers in oncology2023

Pulmonary blastoma treatment response to anti-PD-1 therapy: a rare case report and literature review.

Yalin Xie, Ning Su, Chaoxia Li, An Lei, Lei Li, Jianjun Zou, Wencang Cen, Jinxing Hu

Open access · goldAbstract readCase Reports
In one paragraph

Article in Frontiers in oncology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
2.2field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 7 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Yalin XieDepartment of Oncology, Guangzhou Chest Hospital, Guangzhou, China.
Ning SuDepartment of Oncology, Guangzhou Chest Hospital, Guangzhou, China.
Chaoxia LiDepartment of Pathology, Guangzhou Chest Hospital, Guangzhou, China.
An LeiDepartment of Oncology, Guangzhou Chest Hospital, Guangzhou, China.
Lei LiDepartment of Oncology, Guangzhou Chest Hospital, Guangzhou, China.
Jianjun ZouDepartment of Oncology, Guangzhou Chest Hospital, Guangzhou, China.
Wencang CenDepartment of Oncology, Guangzhou Chest Hospital, Guangzhou, China.
Jinxing HuDepartment of Internal Medicine, Guangzhou Chest Hospital, Guangzhou, China.
Guangzhou Chest Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Pulmonary blastoma (PB) is a rare and invasive malignancy of the lungs with a poor prognosis. Although the mainstay treatment of PB is surgery, and radiotherapy and chemotherapy have been reported, no standard therapy exists for patients inoperable in advanced stages. Moreover, little is known about driver mutation status and immunotherapy efficacy. This paper presents a male patient diagnosed with classic biphasic PB using CT-guided lung biopsy pathology and immunohistochemistry. The patient's symptoms included cough, chest pain, shortness of breath, hemoptysis, and hypodynamia. The primary focus of this paper is to discuss the impact of anti-PD-1 immunotherapy on PB. The patient experienced progression-free survival (PFS) of over 27 months following sintilimab second-line anti-PD-1 therapy. The patient has currently survived for nearly 40 months with a satisfactory quality of life.

Indexed as

checkpoint inhibitionimmunotherapyPD-1/PD-L1 axispulmonary blastomasintilimab

Identifiers

PMID37124510
PMCPMC10130361
OpenAlexW4365148876

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.