ArticleNational science review2023
Hologenomic insights into mammalian adaptations to myrmecophagy.
Article in National science review, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
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Who cites it
21 citing papers in PubMed.
- Animal gut microbes and microbiomes in the 21st century and beyond.Science China. Life sciences · 2026Review
- Beyond mammals: the evolution of chewing and other forms of oropharyngeal food processing in vertebrates.Biological reviews of the Cambridge Philosophical Society · 2026Review
- Pangolin museum genomics reveal the dynamic genetic consequences and extinction risk of the critically endangered Chinese pangolin.Molecular biology and evolution · 2026Article
- Effects of dietary chitin supplementation on body weight, haematology and serum biochemistry, fecal scores and gut microbiota of captive pangolins.Animal microbiome · 2026Article
- Article
- Genomic Insights Into Carnivorous Fish in the Characiformes.Ecology and evolution · 2026Article
- Gut microbiome plasticity explains the altitudinal distribution pattern and adaptability in a small mammal species (Microbiology spectrum · 2026Article
- EHItk: a toolkit for accessing Earth Hologenome Initiative data resources.Bioinformatics advances · 2026Article
- Peptide Mass Fingerprinting of South American Xenarthrans: A New Resource for Zooarcheology and Palaeontology.Journal of proteome research · 2025Article
- Hologenomics Reveals Specialized Dietary Adaptations in the Mengla Snail-Eating Snake.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025Article
- Transcriptomic Data Reveal Divergent Paths of Chitinase Evolution Underlying Dietary Convergence in Anteaters and Pangolins.Genome biology and evolution · 2025Article
- Metabolic diversity and responses of anteater clostridial isolates to chitin-based substrates.Frontiers in veterinary science · 2025Article
- Comparative Metagenomic Analysis of the Gut Microbiota of Captive Pangolins: A Case Study of Two Species.Animals : an open access journal from MDPI · 2024Article
- Genomic signatures of sensory adaptation and evolution in pangolins.BMC genomics · 2024Article
- The Chinese longsnout catfish genome provides novel insights into the feeding preference and corresponding metabolic strategy of carnivores.Genome research · 2024Article
- Microbiome composition and presence of cultivable commensal groups of Southern Tamanduas (Tamandua tetradactyla) varies with captive conditions.Animal microbiome · 2024Article
- Convergence of gut microbiota in myrmecophagous amphibians.Proceedings. Biological sciences · 2023Article
- Metagenomics uncovers dietary adaptations for chitin digestion in the gut microbiota of convergent myrmecophagous mammals.mSystems · 2023Article
- Phylogenetic signal in gut microbial community rather than in rodent metabolic traits.National science review · 2023Article
- Evolutionary activation of acidic chitinase in herbivores through the H128R mutation in ruminant livestock.iScience · 2023Article
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Authors and funding
13 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Highly specialized myrmecophagy (ant- and termite-eating) has independently evolved multiple times in species of various mammalian orders and represents a textbook example of phenotypic evolutionary convergence. We explored the mechanisms involved in this unique dietary adaptation and convergence through multi-omic analyses, including analyses of host genomes and transcriptomes, as well as gut metagenomes, in combination with validating assays of key enzymes' activities, in the species of three mammalian orders (anteaters, echidnas and pangolins of the orders Xenarthra, Monotremata and Pholidota, respectively) and their relatives. We demonstrate the complex and diverse interactions between hosts and their symbiotic microbiota that have provided adaptive solutions for nutritional and detoxification challenges associated with high levels of protein and lipid metabolisms, trehalose degradation, and toxic substance detoxification. Interestingly, we also reveal their spatially complementary cooperation involved in degradation of ants' and termites' chitin exoskeletons. This study contributes new insights into the dietary evolution of mammals and the mechanisms involved in the coordination of physiological functions by animal hosts and their gut commensals.
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