ArticleBiological psychiatry global open science2023
Mapping Normative Trajectories of Cognitive Function and Its Relation to Psychopathology Symptoms and Genetic Risk in Youth.
Article in Biological psychiatry global open science, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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Who cites it
12 citing papers in PubMed.
- Disorder-Specific Genetic Effects Drive the Associations Between Psychopathology and Cognitive Functioning.Biological psychiatry global open science · 2026Article
- Predicting developmental norms from baseline cortical thickness in longitudinal studies.Biology of sex differences · 2026Article
- Childhood exposure to particulate matter and nitrogen oxides and associations with mental health disorders in early adulthood: testing mediation by cognition in a UK longitudinal cohort study.BMJ mental health · 2025Article
- Longitudinal Development of Neurocognitive Functioning and Gray Matter Volume in Youths With Recurrent Psychosis Spectrum Symptoms.Schizophrenia bulletin · 2025Article
- Learning Latent Profiles via Cognitive Growth Charting in Psychosis: Design and Rationale for the PRECOGNITION Project.Schizophrenia bulletin open · 2025Article
- Longitudinal variation in resilient psychosocial functioning is associated with ongoing cortical myelination and functional reorganization during adolescence.Nature communications · 2024Article
- Linking sarcopenia, brain structure and cognitive performance: a large-scale UK Biobank study.Brain communications · 2024Article
- Shared pattern of impaired social communication and cognitive ability in the youth brain across diagnostic boundaries.Developmental cognitive neuroscience · 2023Article
- Evidence for embracing normative modeling.eLife · 2023Article
- Continuity versus change in latent profiles of emotion regulation and working memory during adolescence.Developmental cognitive neuroscience · 2022Article
- Deviations from normative brain white and gray matter structure are associated with psychopathology in youth.Developmental cognitive neuroscience · 2022Article
- Current Evidence and Theories in Understanding the Relationship between Cognition and Depression in Childhood and Adolescence: A Narrative Review.Diagnostics (Basel, Switzerland) · 2022Review
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Authors and funding
12 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Adolescence hosts a sharp increase in the incidence of mental disorders. The prodromal phases are often characterized by cognitive deficits that predate disease onset by several years. Characterization of cognitive performance in relation to normative trajectories may have value for early risk assessment and monitoring. Methods: Youth aged 8 to 21 years ( Results: More negative normative cognitive deviations were associated with higher general psychopathology burden and domains reflecting positive and prodromal psychosis, attention problems, norm-violating behavior, and anxiety. In addition, better performance was associated with higher joint burden of depression, suicidal ideation, and negative psychosis symptoms. The analyses revealed no evidence for associations with polygenic scores. Conclusions: Our results show that cognitive performance is associated with general and specific domains of psychopathology in youth. These findings support the close links between cognition and psychopathology in youth and highlight the potential of normative modeling for early risk assessment.
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