Giant malignant phyllodes tumor with distant metastases: a case report and review of the literature.

A Syrnioti, T Koletsa, S Netta, A Gkoudina, D Paramythiotis

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In one paragraph

Article in Hippokratia. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed

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1 · What the graph read from it

What it found

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5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

A SyrniotiDepartment of Pathology, School of Medicine, Aristotle University of Thessaloniki, Thessaloniki, Greece.

T KoletsaDepartment of Pathology, School of Medicine, Aristotle University of Thessaloniki, Thessaloniki, Greece.

S NettaFirst Propedeutic Department of Surgery, AHEPA University Hospital, School of Medicine, Aristotle University of Thessaloniki, Thessaloniki, Greece.

A GkoudinaFirst Propedeutic Department of Surgery, AHEPA University Hospital, School of Medicine, Aristotle University of Thessaloniki, Thessaloniki, Greece.

D ParamythiotisFirst Propedeutic Department of Surgery, AHEPA University Hospital, School of Medicine, Aristotle University of Thessaloniki, Thessaloniki, Greece.

Aristotle University of Thessaloniki · GR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPhyllodes tumors (PTs) represent a rare type of breast tumor and are classified into benign, borderline, and malignant. Giant PTs, meaning those sized more than ten cm, are even rarer, most commonly malignant, and usually have a dismal prognosis due to the high metastatic potential. CASE REPORT: We report the case of a 55-year-old woman who underwent modified radical mastectomy and left axillary lymphadenectomy for a rapidly growing, giant, ulcerated mass of the left breast. Histopathologic examination revealed a malignant phyllodes tumor (MPT). Over one year after the initial surgery, the patient was found to have extensive thoracic and retroperitoneal metastases.

conclusionAlthough giant PTs are uncommon, clinical suspicion should be high in rapidly growing breast mass patients. A comprehensive review of all metastatic giant MPT cases reported in the English literature emphasizes the lack of consensus regarding appropriate treatment. In the case of metastatic foci, pathologists need to be aware of the previous history to make a definitive diagnosis. Also, a comparative histopathologic study of the primary and metastatic tumors is sometimes necessary. HIPPOKRATIA 2022, 26 (1):41-45.

Indexed as

Biphasic breast tumorbreast tumorsgiant phyllodes tumormalignant fibroepithelial tumormetastatic breast tumormetastatic phyllodes tumor

Identifiers

PMID37124283

PMCPMC10132391

OpenAlexW4367601468

What OpenQuestion holds

Textmetadata

Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.