Evidence map›Paper›PMID 37124005›Full record

ArticleRSC advances2023

Functionalized bioadhesion-enhanced carboxymethyl cellulose/polyvinyl alcohol hybrid hydrogels for chronic wound dressing applications.

A A P Mansur, M A Rodrigues, N S V Capanema, S M Carvalho, D A Gomes, H S Mansur

Open access · goldAbstract read
In one paragraph

Article in RSC advances, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
3.9field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 28 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. One-Pot Synthesis of Antibacterial and Antioxidant Self-Healing Bioadhesives Using Ugi Four-Component Reactions.Journal of biomedical materials research. Part B, Applied biomaterials · 2025
    Article
  5. Review
  6. Article
  7. Article
  8. Review
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

A A P MansurDepartment of Metallurgical and Materials Engineering, Center of Nanoscience, Nanotechnology and Innovation - CeNano2I, Federal University of Minas Gerais Av. Antônio Carlos 6627 - Escola de Engenharia, Bloco 2 - Sala 2233, 31.270-901 Belo Horizonte MG Brazil hmansur@demet.ufmg.br +55-31-34091843.
M A RodriguesDepartment of Biochemistry and Immunology, Federal University of Minas Gerais Brazil.
N S V CapanemaDepartment of Metallurgical and Materials Engineering, Center of Nanoscience, Nanotechnology and Innovation - CeNano2I, Federal University of Minas Gerais Av. Antônio Carlos 6627 - Escola de Engenharia, Bloco 2 - Sala 2233, 31.270-901 Belo Horizonte MG Brazil hmansur@demet.ufmg.br +55-31-34091843.
S M CarvalhoDepartment of Metallurgical and Materials Engineering, Center of Nanoscience, Nanotechnology and Innovation - CeNano2I, Federal University of Minas Gerais Av. Antônio Carlos 6627 - Escola de Engenharia, Bloco 2 - Sala 2233, 31.270-901 Belo Horizonte MG Brazil hmansur@demet.ufmg.br +55-31-34091843.
D A GomesDepartment of Biochemistry and Immunology, Federal University of Minas Gerais Brazil.
H S MansurDepartment of Metallurgical and Materials Engineering, Center of Nanoscience, Nanotechnology and Innovation - CeNano2I, Federal University of Minas Gerais Av. Antônio Carlos 6627 - Escola de Engenharia, Bloco 2 - Sala 2233, 31.270-901 Belo Horizonte MG Brazil hmansur@demet.ufmg.br +55-31-34091843.ORCID https://orcid.org/0000-0002-3032-495X
Universidade Federal de Minas Gerais · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Wounds produced by trauma, burns, and chronic diseases cause millions of patients to suffer discomfort, pain, and, in many cases, disability and death, leading to enormous health, social and financial impacts globally. Regrettably, current clinical treatments for chronic wounds remain unsatisfactory. Thus, this study reports for the first time the design, development, and synthesis of chemically biofunctionalized hybrid hydrogels made of carboxymethyl cellulose (CMC) and poly(vinyl alcohol) (PVA) crosslinked by citric acid using an entirely biocompatible and green process. They demonstrated suitable physicochemical properties, cytocompatibility, and hemocompatibility to be applied as a smart wound dressing for skin tissue engineering. These novel hybrids were biofunctionalized with l-arginine and RGD peptide through carbodiimide mediated-amide formation to promote bioadhesion of fibroblast and keratinocyte cells as a potential enhancement for wound healing and skin tissue engineering applications.

Identifiers

PMID37124005
PMCPMC10140670
OpenAlexW4367336141

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.