Evidence map›Paper›PMID 37123551›Full record

ArticleHealth science reports2023

Effect of magnesium sulfate treatment on mediators of endothelial dysfunction and electrolytes in mild and severe preeclampsia: A case-control study.

Linda A Fondjo, Davis Sarpong, William K B A Owiredu, Stephen Opoku, Kwame Adu-Bonsaffoh, Emmanuel Teviu

Registry-linked trialAbstract read
In one paragraph

Article in Health science reports, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06437535 (The Pathophysiological Role of Vaspin and Apoptosis in Pre-eclamptic Obese Women), which is not on this map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06437535 unknown statusnot on this mapstarted 2024, after this paper: background citation

The Pathophysiological Role of Vaspin and Apoptosis in Pre-eclamptic Obese Women

TypeobservationalSponsorAssiut UniversityRan2024 to 2025Enrolled75ConditionsPre-Eclampsia
3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Linda A FondjoDepartment of Molecular Medicine, School of Medicine and Dentistry Kwame Nkrumah University of Science and Technology Kumasi Ghana.ORCID 0000-0003-0252-3190
Davis SarpongDepartment of Molecular Medicine, School of Medicine and Dentistry Kwame Nkrumah University of Science and Technology Kumasi Ghana.
William K B A OwireduDepartment of Molecular Medicine, School of Medicine and Dentistry Kwame Nkrumah University of Science and Technology Kumasi Ghana.
Stephen OpokuDepartment of Medical Diagnostics, Faculty of Allied Health Sciences Kwame Nkrumah University of Science and Technology Kumasi Ghana.
Kwame Adu-BonsaffohDepartment of Obstetrics Gynaecology University of Ghana Medical School Accra Ghana.
Emmanuel TeviuSampa Government Hospital Western Region Ghana.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background and Aims: Magnesium sulfate (MgSO Methods: We recruited 100 women comprising 50 severe, 50 mild preeclampsia (PE) as cases and 50 normotensive pregnant women as controls from the Sampa Government Hospital, Ghana. We estimated for adrenomedullin (AM), calcitonin gene-related peptide (CGRP), soluble forms of intercellular adhesion molecule-1 (sICAM-1), Na Results: Levels of AM, sICAM-1, and Na Conclusion: MgSO₄ treatment reduces AM, sICAM-1, and sodium levels but improves magnesium and CGRP in severe than mild PE thus have more beneficial role in severe PE.

Indexed as

adrenomedullincalcitonin gene‐related peptideelectrolytesendothelial dysfunctionmagnesium sulfateMgpreeclampsiasoluble forms of intercellular adhesion molecule‐1

Identifiers

PMID37123551
PMCPMC10130740

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.