Evidence map›Paper›PMID 37123538›Full record

ArticlePulmonary circulation2023

Multiomics endotyping of preterm infants with bronchopulmonary dysplasia and pulmonary hypertension-A pilot study.

Roopa Siddaiah, Christiana Oji-Mmuo, Vincent P R Aluquin, Yuka Imamura Kawasawa, Ann Donnelly, Dustin Rousselle, Nathalie Fuentes, Eric D Austin, Patricia Silveyra

Open access · goldAbstract read
In one paragraph

Article in Pulmonary circulation, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
2.1field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Phenotype-based screening algorithm for chronic pulmonary hypertension in preterm infants with bronchopulmonary dysplasia.Journal of perinatology : official journal of the California Perinatal Association · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Roopa SiddaiahDepartment of Pediatrics Penn State Health Children's Hospital Hershey Pennsylvania USA.ORCID 0000-0001-9184-3908
Christiana Oji-MmuoDepartment of Pediatrics Penn State Health Children's Hospital Hershey Pennsylvania USA.ORCID 0000-0002-8897-9203
Vincent P R AluquinDepartment of Pediatrics Penn State Health Children's Hospital Hershey Pennsylvania USA.
Yuka Imamura KawasawaDepartment of Pharmacology Penn State Health Children's Hospital Hershey Pennsylvania USA.
Ann DonnellyDepartment of Respiratory Therapy Penn State Health Children's Hospital Hershey Pennsylvania USA.
Dustin RousselleDepartment of Environmental and Occupational Health Indiana University School of Public Health Bloomington Indiana USA.
Nathalie FuentesDepartment of Pediatrics Penn State Health Children's Hospital Hershey Pennsylvania USA.
Eric D AustinDepartment of Pediatrics Vanderbilt University Nashville Tennessee USA.
Patricia SilveyraDepartment of Pediatrics Penn State Health Children's Hospital Hershey Pennsylvania USA.
Penn State Milton S. Hershey Medical Center · USIndiana University Health · USVanderbilt University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Pulmonary hypertension associated with bronchopulmonary dysplasia is a severe complication of preterm birth resulting in high mortality of up to 50% within the first 2 years of life. There is a direct relationship between bronchopulmonary dysplasia severity and incidence of associated pulmonary hypertension. However, it is challenging to clinically characterize severe bronchopulmonary dysplasia with and without pulmonary hypertension and there is need for better understanding of the two entities. Our main objective is to identify markers to help understand biological processes and characterize infants with pulmonary hypertension associated with bronchopulmonary dysplasia using tracheal aspirates. We conducted an unbiased multiomic analysis of tracheal aspirates via microRNA (miRNA) polymerase chain reaction arrays, RNA sequencing, and mass spectrometry proteomics in preterm infants with severe bronchopulmonary dysplasia with and without pulmonary hypertension (

Indexed as

bronchopulmonary dysplasiamultiomicspreterm infantspulmonary hypertensiontracheal aspirate

Identifiers

PMID37123538
PMCPMC10142061
OpenAlexW4366281462

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.