The efficacy of antibiotic-impregnated calcium sulfate (AICS) in the treatment of infected non-union and fracture-related infection: a systematic review.

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

Who cites it

10 citing papers in PubMed, 11 citations in OpenAlex.

1. A Novel Gelatin Hydrogel-Based Drug-Delivery System Promotes Antimicrobial Efficacy in a Pyogenic Spondylodiscitis Rat Model.JOR spine · 2026
   Article
2. Outcomes and safety of antibiotic-loaded calcium sulfate beads in orthopaedics: A systematic review and meta-analysis.Journal of orthopaedics · 2026
   Review
3. Proximal Femoral Replacement for Infected Non-union of the Proximal Femur With Adherent Femoral Artery: Surgical Challenges and Techniques to Minimize Vascular Risk.Cureus · 2026
   Article
4. Strategic considerations in the treatment of infected nonunion in the lower extremity: a narrative review.International journal of surgery (London, England) · 2026
   Article
5. Managing Nonunions and Fracture-Related Infections-A Quarter Century of Knowledge, and Still Curious: A Narrative Review.Journal of clinical medicine · 2025
   Review
6. [Recent advances regarding diagnosis and treatment of fracture-related infection].Zhongguo xiu fu chong jian wai ke za zhi = Zhongguo xiufu chongjian waike zazhi = Chinese journal of reparative and reconstructive surgery · 2025
   Review
7. Case Commentary: A herculean effort forAntimicrobial agents and chemotherapy · 2025
   Article
8. The immediate ex vivo covering and filling characteristics of antibiotic-loaded resorbable calcium sulfate paste around intramedullary nails.Journal of bone and joint infection · 2024
   Article
9. Surgical site application of antibiotics: A potential game changer for fracture-related infection care and antibiotic stewardship.Journal of orthopaedics · 2023
   Article
10. Local Antibiotic Delivery Systems and Their Applications in Orthopaedic Surgery.JB & JS open access
    Review

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

Authors and funding

3 authors at 1 institution in 1 country.

Funding

No grant is acknowledged in the PubMed record.

Abstract

PubMed holds no abstract for this paper.