Evidence map›Paper›PMID 37123414›Full record

ReviewFrontiers in cell and developmental biology2023

Autophagy in graves' ophthalmopathy.

Yu-Qing Chen, Lian-Di Gao, Yi-Lin Liu, Ya Shen, Jia-Le Diao, Wei-Hua Yang, Rui-Li Wei

Open access · goldAbstract readReview
In one paragraph

Review in Frontiers in cell and developmental biology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.4field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. The role of autophagy in Graves disease: knowns and unknowns.Frontiers in cell and developmental biology · 2024
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Yu-Qing ChenDepartment of Ophthalmology, Changzheng Hospital of Naval Medicine University, Shanghai, China.
Lian-Di GaoDepartment of Nursing, Changzheng Hospital of Naval Medicine University, Shanghai, China.
Yi-Lin LiuDepartment of Nursing, Changzheng Hospital of Naval Medicine University, Shanghai, China.
Ya ShenDepartment of Ophthalmology, Changzheng Hospital of Naval Medicine University, Shanghai, China.
Jia-Le DiaoDepartment of Ophthalmology, Changzheng Hospital of Naval Medicine University, Shanghai, China.
Wei-Hua YangShenzhen Eye Hospital, Jinan University, Shenzhen, China.
Rui-Li WeiDepartment of Ophthalmology, Changzheng Hospital of Naval Medicine University, Shanghai, China.
Second Military Medical University · CNShanghai Changzheng Hospital · CNJinan University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Graves' ophthalmopathy (GO) is an inflammatory autoimmune disease that affects the eyes. It can significantly alter the quality of life in patients because of its distinctive pathological appearance and the effect on vision. To date, the exact pathological mechanism of GO has not been explicitly discovered. However, several studies have associated autophagy with this disease. Autophagy is a catabolic process that helps maintain homeostasis in all organisms by protecting the cells and tissues from various endogenous and exogenous stress factors. Based on our results, patients affected with GO have comparatively elevated levels of autophagy, which critically affects the pathological mechanism of the GO. In this review, we have summarized the autophagy mechanism in the pathogenesis of GO.

Indexed as

adipogenesisautophagyglycosaminoglycangraves’ ophthalmopathyinflammation

Identifiers

PMID37123414
PMCPMC10140433
OpenAlexW4365515932

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.