Evidence map›Paper›PMID 37123399›Full record

ArticleFrontiers in cell and developmental biology2023

The environmental stress response regulates ribosome content in cell cycle-arrested

Allegra Terhorst, Arzu Sandikci, Charles A Whittaker, Tamás Szórádi, Liam J Holt, Gabriel E Neurohr, Angelika Amon

Open access · goldAbstract read
In one paragraph

Article in Frontiers in cell and developmental biology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
2.6field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 18 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

Allegra TerhorstDavid H. Koch Institute for Integrative Cancer Research, Howard Hughes Medical Institute, Massachusetts Institute of Technology, Cambridge, MA, United States.
Arzu SandikciDavid H. Koch Institute for Integrative Cancer Research, Howard Hughes Medical Institute, Massachusetts Institute of Technology, Cambridge, MA, United States.
Charles A WhittakerDavid H. Koch Institute for Integrative Cancer Research, Howard Hughes Medical Institute, Massachusetts Institute of Technology, Cambridge, MA, United States.
Tamás SzórádiInstitute for Systems Genetics, New York University Langone Health, New York City, NY, United States.
Liam J HoltInstitute for Systems Genetics, New York University Langone Health, New York City, NY, United States.
Gabriel E NeurohrDavid H. Koch Institute for Integrative Cancer Research, Howard Hughes Medical Institute, Massachusetts Institute of Technology, Cambridge, MA, United States.
Angelika AmonDavid H. Koch Institute for Integrative Cancer Research, Howard Hughes Medical Institute, Massachusetts Institute of Technology, Cambridge, MA, United States.
Howard Hughes Medical Institute · USNYU Langone Health · USMassachusetts Institute of Technology · US

Funding

VIRUS PRODUCTION COREP30CA014051 · NCI · MASSACHUSETTS INSTITUTE OF TECHNOLOGY · PI Paula T Hammond · 1985 to 2026
$93.9M
The Physical Biology of Neurodegeneration in Sporadic Amyotrophic Lateral Sclerosis/Frontotemporal DementiaR01NS127186 · NINDS · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI HOLT, LIAM J, PHATNANI, HEMALI · 2021 to 2025
$8.2M
Cancer under pressure: Mechanisms of adaptation to compressive stressR37CA240765 · NCI · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI HOLT, LIAM J · 2019 to 2025
$3.2M
Tools to probe the biophysical properties of cellsR01GM132447 · NIGMS · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI HOLT, LIAM J · 2019 to 2022
$2.1M
Causes and consequences of aneuploidyR35GM118066 · NIGMS · MASSACHUSETTS INSTITUTE OF TECHNOLOGY · PI AMON, ANGELIKA B · 2016 to 2020
$1.9M
Regulation of mitosis by proteolysis in yeastR01CA206157 · NCI · MASSACHUSETTS INSTITUTE OF TECHNOLOGY · PI AMON, ANGELIKA B · 2016 to 2020
$1.4M
NCI NIH HHS P30 CA014051NCI NIH HHS R01 CA206157NCI NIH HHS R37 CA240765NIGMS NIH HHS R01 GM132447NIGMS NIH HHS R35 GM118066NINDS NIH HHS R01 NS127186
6 · The paper itself

Abstract

Prolonged cell cycle arrests occur naturally in differentiated cells and in response to various stresses such as nutrient deprivation or treatment with chemotherapeutic agents. Whether and how cells survive prolonged cell cycle arrests is not clear. Here, we used

Indexed as

cell cycle arrestcytoplasm dilutionenvironmental stress response (ESR)growth lawribosome fraction

Identifiers

PMID37123399
PMCPMC10130656
OpenAlexW4365149205

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.