ArticleArchives of Razi Institute2022
The Association of Serum Calcium and Vitamin D with Insulin Resistance and Beta-Cell Dysfunction among People with Type 2 Diabetes.
Article in Archives of Razi Institute, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
4 citing papers in PubMed, 1 synthesis or guideline pooled it, 8 citations in OpenAlex.
- The association between insulin resistance and QT interval: A systematic review and Meta-Analysis.BMC cardiovascular disorders · 2025Pooled it
- Supplementing 25-Hydroxy-Vitamin DAnimals : an open access journal from MDPI · 2025Article
- Investigation of the association between total dietary calcium intake and its various sources with type 2 diabetes: Tehran lipid and glucose study.Nutrition & metabolism · 2025Article
- Article
Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Cross-sectional studies have linked vitamin D deficiency and alteration of calcium levels to an increased incidence of type 2 diabetes and insulin resistance. This study investigated a possible correlation between blood vitamin D and calcium levels with insulin resistance and beta-cell dysfunction in type 2 diabetes, pre-diabetes, and healthy individuals. This cross-sectional study involved 300 participants. Participants were divided into three groups (n=100), type 2diabetic, prediabetic, and healthy. In order to measure insulin resistance and β -cell function, the HOMA IR and HOMA B were assessed, respectively. Also, the other parameters such as serum 25(OH)D, blood insulin (FPI), glucose (FBS), HbA1c, and calcium were assessed in this study. In simple regression analysis, a high vitamin D level is linked to lower levels of FBS, HbA1c, Insulin, and HOMA IR, and higher levels of HOMA B. Calcium has a positive connection with FBS and HbA1c and a negative connection with insulin level and HOMAB. Hypovitaminosis D may substantially influence diabetes patients' glycemic dysregulation. "An increased incidence of type 2 diabetes has been related to a disruption in calcium homeostasis. All in all an increament in calcium levels may have a role in developing type 2 diabetes".
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.