Evidence map›Paper›PMID 37122918›Full record

ArticleData in brief2023

Mechanical characterization data of polyacrylamide hydrogel formulations and 3D printed PLA for application in human head phantoms.

Anthony J A Baker, Eric J Galindo, James D Angelos, Dustin K Salazar, Sorcha M Sterritt, Adam M Willis, Michaelann S Tartis

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Data in brief, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Anthony J A BakerNew Mexico Institute of Mining and Technology, Department of Chemical Engineering, 801 Leroy Place, Socorro, NM 87801, USA.
Eric J GalindoNew Mexico Institute of Mining and Technology, Department of Chemical Engineering, 801 Leroy Place, Socorro, NM 87801, USA.
James D AngelosNew Mexico Institute of Mining and Technology, Department of Chemical Engineering, 801 Leroy Place, Socorro, NM 87801, USA.
Dustin K SalazarNew Mexico Institute of Mining and Technology, Department of Chemical Engineering, 801 Leroy Place, Socorro, NM 87801, USA.
Sorcha M SterrittNew Mexico Institute of Mining and Technology, Department of Chemical Engineering, 801 Leroy Place, Socorro, NM 87801, USA.
Adam M WillisMichigan State University, Department of Mechanical Engineering, East Lansing MI, 48824, USA.
Michaelann S TartisNew Mexico Institute of Mining and Technology, Department of Chemical Engineering, 801 Leroy Place, Socorro, NM 87801, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

To study human traumatic brain injury (TBI) mechanics, a realistic surrogate must be developed for testing in impact experiments. In this data brief, materials used to simulate brain tissue and skull are characterized for application in a full-scale human head phantom. Polyacrylamide hydrogels are implemented as tissue scaffolds and tissue mimics because they are bioinert and tunable. These properties make them ideal for use as brain tissue in studies that simulate head impacts. The objective is to modify hydrogel formulations to have minimal swelling and optical clarity while maintaining properties that mimic brain tissue, such as density, viscoelastic properties, and rheological properties. Secondly, polylactic acid (PLA) polymers are 3D printed to create biomimetic skulls to enclose the hydrogel brain tissue mimic or brain phantom. PLA samples are printed and tested to determine their mechanical strength with the intention of roughly matching human skull properties. Hydrogel data was obtained with an oscillatory rheometer, while PLA samples were tested using a mechanical tester with a 3-point bend setup. The present data brief highlights several hydrogel formulations and compares them to identify the benefits of each formula and reports mechanical values of 3D printed PLA samples with 100% grid infill patterns applied in a skull model.

Indexed as

3D PrintingBrain phantomBrain tissueHydrogelMechanical testingPolyacrylamide (PAA)Polylactic acid (PLA)RheologySkull

Identifiers

PMID37122918
PMCPMC10130753

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.