Evidence map›Paper›PMID 37122729›Full record

ArticleFrontiers in immunology2023

A crucial exosome-related gene pair (

Huiyong Ren, Yumin Li, Hao Liu, Jiaxin Fan, Jie Li, Haopeng Li, Hongyu Wei, Liesu Meng, Shuai Cao

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in immunology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.5field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 1 country.

Huiyong RenDepartment of Orthopedics, Civil Aviation General Hospital, Beijing, China.
Yumin LiDepartment of Orthopedics, Civil Aviation General Hospital, Beijing, China.
Hao LiuDepartment of Orthopaedics, The Second Affiliated Hospital of Xi'an Jiaotong University, Xi'an, Shanxi, China.
Jiaxin FanDepartment of Neurology, The Second Affiliated Hospital of Xi'an Jiaotong University, Xi'an, China.
Jie LiDepartment of Orthopaedics, The Second Affiliated Hospital of Xi'an Jiaotong University, Xi'an, Shanxi, China.
Haopeng LiDepartment of Orthopaedics, The Second Affiliated Hospital of Xi'an Jiaotong University, Xi'an, Shanxi, China.
Hongyu WeiDepartment of Orthopaedic Surgery, China-Japan Friendship Hospital, Beijing, China.
Liesu MengInstitute of Molecular and Translational Medicine (IMTM), and Department of Biochemistry and Molecular Biology, School of Basic Medical Sciences, Xi'an Jiaotong University Health Science Center, Xi'an, China.
Shuai CaoDepartment of Orthopedics, Civil Aviation General Hospital, Beijing, China.
Second Affiliated Hospital of Xi'an Jiaotong University · CNAviation General Hospital · CNChina-Japan Friendship Hospital · CNXi'an Jiaotong University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Identification of exosome-related genes (ERGs) and competing endogenous RNAs (ceRNAs) associated with intervertebral disc degeneration (IDD) may improve its diagnosis and reveal its underlying mechanisms. We downloaded 49 samples from Gene Expression Omnibus and identified candidate ERGs using differentially expressed ERGs (De-ERGs), exosome-related gene pairs (ERGPs), and machine learning algorithms [least absolute shrinkage and selection operator (LASSO) and support vector machine (SVM)]. Immune cell-related ERGs were selected

Indexed as

4-Aminobutyrate TransaminaseExosomesIntervertebral Disc DegenerationAdaptor Proteins, Signal TransducingHumansSignal Transduction4-Aminobutyrate TransaminaseAAMP protein, humanAdaptor Proteins, Signal Transducingexosomesgene pairsimmune infiltrationIntervertebral disc degenerationmachine learning

Identifiers

PMID37122729
PMCPMC10140513
OpenAlexW4365515735

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.