Evidence map›Paper›PMID 37122704›Full record

ArticleFrontiers in immunology2023

Mercury increases IL-1β and IL-18 secretion and intensifies coronary arteritis in an animal model of Kawasaki disease.

Martin P Alphonse, Trang T Duong, Suzanne Tam, Rae S M Yeung

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in immunology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
3.2field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Article
  5. Tattoo inks: evaluation of cellular responses and analysis of some trace metals.Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine · 2024
    Article
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 2 countries.

Martin P AlphonseCell Biology Research Program, The Hospital for Sick Children Research Institute, Toronto, ON, Canada.
Trang T DuongCell Biology Research Program, The Hospital for Sick Children Research Institute, Toronto, ON, Canada.
Suzanne TamCell Biology Research Program, The Hospital for Sick Children Research Institute, Toronto, ON, Canada.
Rae S M YeungCell Biology Research Program, The Hospital for Sick Children Research Institute, Toronto, ON, Canada.
Hospital for Sick Children · CAJohns Hopkins Medicine · USUniversity of Toronto · CA

Funding

CIHR FRN111248
6 · The paper itself

Abstract

Kawasaki disease (KD) is a multisystem vasculitis that predominantly targets the coronary arteries in young children. Epidemiological data suggest both environmental and genetic factors contribute to the susceptibility and severity of the disease. Mercury (Hg) is a known environmental pollutant and a Ca

Indexed as

ArteritisCoronary Artery DiseaseLacticaseibacillus caseiMercuryMucocutaneous Lymph Node SyndromeAnimalsDisease Models, AnimalInflammasomesInterleukin-18MiceInflammasomesInterleukin-18Mercurycalcium signalingcoronary arteritisinflammasomeinflammationITPKC/IP3-3KC/IP3KCKawasaki disease (KD)mercuryNLRP3 inflammasome

Identifiers

PMID37122704
PMCPMC10140582
OpenAlexW4365515688

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.