Evidence map›Paper›PMID 37122605›Full record

ArticleWorld journal of gastroenterology2023

Changes in the gut mycobiome in pediatric patients in relation to the clinical activity of Crohn's disease.

Agnieszka Krawczyk, Dominika Salamon, Kinga Kowalska-Duplaga, Barbara Zapała, Teofila Książek, Marta Drażniuk-Warchoł, Tomasz Gosiewski

Abstract read
In one paragraph

Article in World journal of gastroenterology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Extracellular vesicles produced byExtracellular vesicles and circulating nucleic acids · 2026
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  4. Gut and skin dysbiosis in acne vulgaris: a comparative microbiome analysis.Frontiers in cellular and infection microbiology · 2026
    Article
  5. Article
  6. Article
  7. Article
  8. Review
  9. The Gut Mycobiome for Precision Medicine.Journal of fungi (Basel, Switzerland) · 2025
    Review
  10. Role ofWorld journal of gastroenterology · 2024
    Review
  11. Role of fungus in inflammatory bowel disease: The butterfly effect?Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology · 2024
    Article
  12. Article
  13. A comprehensive guide to assess gut mycobiome and its role in pathogenesis and treatment of inflammatory bowel disease.Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology · 2024
    Review
  14. Review
  15. Review
  16. Article
  17. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Agnieszka KrawczykDepartment of Microbiology, Division of Molecular Medical Microbiology, Jagiellonian University Medical College, Cracow 31-121, Poland.
Dominika SalamonDepartment of Microbiology, Division of Molecular Medical Microbiology, Jagiellonian University Medical College, Cracow 31-121, Poland.
Kinga Kowalska-DuplagaDepartment of Pediatrics, Gastroenterology and Nutrition, Jagiellonian University Medical College, Cracow 30-663, Poland.
Barbara ZapałaDepartment of Clinical Biochemistry, Jagiellonian University Medical College, Cracow 31-066, Poland.
Teofila KsiążekDepartment of Medical Genetics, Jagiellonian University Medical College, Cracow 30-663, Poland.
Marta Drażniuk-WarchołDepartment of Pediatrics, Gastroenterology and Nutrition, University Children's Hospital, Cracow 30-663, Poland.
Tomasz GosiewskiDepartment of Microbiology, Division of Molecular Medical Microbiology, Jagiellonian University Medical College, Cracow 31-121, Poland. tomasz.gosiewski@uj.edu.pl.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundNumerous studies have shown that in Crohn's disease (CD), the gut microbiota is of great importance in the induction and maintenance of inflammation in the gastrointestinal tract. Until recently, studies have focused almost exclusively on bacteria in the gut. Lately, more attention has been paid to the role of intestinal fungi.

aimTo study the gut mycobiome analysis of pediatric patients with CD (in different stages of disease activity) compared to healthy children.

methodsFecal samples were collected from patients: With active, newly diagnosed CD (

results

conclusionMycobiome changes in CD patients, and the positive correlation of some species with calprotectin or PCDAI, give strong evidence that fungi may be of key importance in the development of CD.

Indexed as

Crohn DiseaseMycobiomeCandidaChildFecesFungiHumansLeukocyte L1 Antigen ComplexSaccharomycetalesLeukocyte L1 Antigen ComplexCrohn’s diseaseFungiInflammatory bowel diseaseIntestinal mycobiomeMolecular microbiologyNext generation sequencing

Identifiers

PMID37122605
PMCPMC10130967

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.