ArticleACS central science2023
SARS-CoV-2 M
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In one paragraph
Article in ACS central science, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers.
0numbers the graph read from it
0cells of the map it votes in
33citing papers in PubMed
9.4field-weighted citation impact, top 2% of its field
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
33 citing papers in PubMed, 57 citations in OpenAlex.
- SARS-CoV-2 3CL protease interaction with host factors - identifying novel drug targets.Archives of virology · 2026Review
- Protein Large Language Models Can PredictACS omega · 2026Article
- Coupling high-throughput protease enzymology with viral replication reveals biochemical constraints of viral fitness.bioRxiv : the preprint server for biology · 2026Article
- Cooperativity and communication between the active sites of the dimeric SARS-CoV-2 main protease.Science advances · 2026Article
- Differential Impact of Substrate Peptides on Interdomain Interactions in Severe Acute Respiratory Syndrome Coronavirus 2 Main Protease.Computational and structural biotechnology journal · 2026Article
- Structural insights into the nirmatrelvir-resistant SARS-CoV-2 MRSC medicinal chemistry · 2025Article
- Meeting report: 38th international conference on antiviral research in Las Vegas, United States of America, March 17-21, 2025.Antiviral research · 2025Article
- Targeting SARS-CoV-2 main protease: a pharmacophore and molecular modeling approach.Journal of molecular modeling · 2025Article
- Identification of naturally occurring drug-resistant mutations of SARS-CoV-2 papain-like protease.Nature communications · 2025Article
- Molecular Recognition of SARS-CoV-2 Mpro Inhibitors: Insights from Cheminformatics and Quantum Chemistry.Molecules (Basel, Switzerland) · 2025Article
- Structure-based discovery of highly bioavailable, covalent, broad-spectrum coronavirus MScience advances · 2025Article
- Profiling of sesquiterpenoid fractions fromBiomolecules & biomedicine · 2025Article
- Exploring Possible Drug-Resistant Variants of SARS-CoV-2 Main Protease (MACS bio & med chem Au · 2025Article
- Distal protein-protein interactions contribute to nirmatrelvir resistance.Nature communications · 2025Article
- The zymogenic form of SARS-CoV-2 main protease: A discrete target for drug discovery.The Journal of biological chemistry · 2025Article
- Factors influencing Nirmatrelvir/Ritonavir concentration in patients with COVID-19.BMC infectious diseases · 2024Article
- Docking heparan sulfate-based ligands as a promising inhibitor for SARS-CoV-2.Journal of molecular modeling · 2024Article
- Revealing SARS-CoV-2 MComputational and structural biotechnology journal · 2024Article
- Large scale analysis of the SARS-CoV-2 main protease reveals marginal presence of nirmatrelvir-resistant SARS-CoV-2 Omicron mutants in Ontario, Canada, December 2021-September 2023.Canada communicable disease report = Releve des maladies transmissibles au Canada · 2024Article
- Structural and virologic mechanism of the emergence of resistance to MProceedings of the National Academy of Sciences of the United States of America · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
19 authors at 2 institutions in 2 countries.
Sizhu Amelia ChenDepartment of Biochemistry, University of Alberta, Edmonton, Alberta T6G 2H7, Canada.
Elena ArutyunovaDepartment of Biochemistry, University of Alberta, Edmonton, Alberta T6G 2H7, Canada.
Jimmy LuDepartment of Biochemistry, University of Alberta, Edmonton, Alberta T6G 2H7, Canada.
Muhammad Bashir KhanDepartment of Biochemistry, University of Alberta, Edmonton, Alberta T6G 2H7, Canada.
Wioletta RutDepartment of Chemical Biology and Bioimaging, Wroclaw University of Science and Technology, Wroclaw, 50-370, Poland.ORCID https://orcid.org/0000-0003-1261-5566
Mikolaj ZmudzinskiDepartment of Chemical Biology and Bioimaging, Wroclaw University of Science and Technology, Wroclaw, 50-370, Poland.ORCID https://orcid.org/0000-0002-9792-9160
Shima ShahbazDepartment of Dentistry & Dental Hygiene, University of Alberta, Edmonton, Alberta T6G 2E1, Canada.
Jegan IyyathuraiDepartment of Biochemistry, University of Alberta, Edmonton, Alberta T6G 2H7, Canada.
Eman W MoussaDepartment of Biochemistry, University of Alberta, Edmonton, Alberta T6G 2H7, Canada.
Zoe TurnerDepartment of Biochemistry, University of Alberta, Edmonton, Alberta T6G 2H7, Canada.ORCID https://orcid.org/0000-0002-3130-5208
Bing BaiLi Ka Shing Applied Virology Institute, University of Alberta, Edmonton, Alberta T6G 2E1, Canada.
Tess LamerDepartment of Chemistry, University of Alberta, Edmonton, Alberta T6G 2G2, Canada.ORCID https://orcid.org/0000-0002-1511-4540
James A NiemanLi Ka Shing Applied Virology Institute, University of Alberta, Edmonton, Alberta T6G 2E1, Canada.ORCID https://orcid.org/0000-0002-5087-0819
John C VederasDepartment of Chemistry, University of Alberta, Edmonton, Alberta T6G 2G2, Canada.ORCID https://orcid.org/0000-0002-2996-0326
Olivier JulienDepartment of Biochemistry, University of Alberta, Edmonton, Alberta T6G 2H7, Canada.ORCID https://orcid.org/0000-0001-7068-7299
Marcin DragDepartment of Chemical Biology and Bioimaging, Wroclaw University of Science and Technology, Wroclaw, 50-370, Poland.ORCID https://orcid.org/0000-0001-8510-1967
Shokrollah ElahiDepartment of Dentistry & Dental Hygiene, University of Alberta, Edmonton, Alberta T6G 2E1, Canada.ORCID https://orcid.org/0000-0002-7215-2009
Howard S YoungDepartment of Biochemistry, University of Alberta, Edmonton, Alberta T6G 2H7, Canada.ORCID https://orcid.org/0000-0002-5990-8422
M Joanne LemieuxDepartment of Biochemistry, University of Alberta, Edmonton, Alberta T6G 2H7, Canada.ORCID https://orcid.org/0000-0003-4745-9153
University of Alberta · CAWrocław University of Science and Technology · PL
Funding
No grant is acknowledged in the PubMed record.
Abstract
The main protease of SARS-CoV-2 (M
Identifiers
What OpenQuestion holds
Textfull text, public
LicenceCC BY
measurements read48
table measurements read1
Read underepoch 390
Registered trials
None linked
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.