Prevalence and factors associated with hyperphosphatemia in continuous ambulatory peritoneal dialysis patients: A cross-sectional study.

Background: Hyperphosphatemia remains a major complication in patients with Continuous ambulatory peritoneal dialysis (CAPD) leading to increased morbidity and mortality. However, phosphorus management still has many challenges. Objective: This study aimed to investigate the prevalence and factors of hyperphosphatemia among continuous ambulatory peritoneal dialysis patients in a tertiary public hospital in Shanghai, China. Methods: The single-center cross-sectional study recruited end-stage renal failure patients who received continuous ambulatory peritoneal dialysis (CAPD) for at least 3 months. The participants aged 18-80 years had undergone CAPD between 1 July 2021 and 30 May 2022, in Shanghai, China.The patients' sociodemographic, clinical, and laboratory data were collected prospectively from medical records and Results: In total, 141 CAPD patients (73% hyperphosphatemia) were included in the final analysis. In logistic regression analysis, dialysis vintage (OR: 0.975, 95%CI: 0.957-0.993), dialysis exchanges (OR: 0.317, 95%CI: 0.131-0.768), urine output (OR: 0.997, 95%CI: 0.995-0.999), serum albumin (OR: 1.166, 95%CI:1.008-1.349), serum creatinine (OR: 1.005, 95%CI: 1.001-1.008), hyperphosphatemia knowledge behavior score (OR: 0.888, 95%CI: 0.797-0.991), and social support level (OR: 0.841, 95%CI:0.765-0.925) were the influencing factors of hyperphosphatemia. Conclusion: Hyperphosphatemia is a frequent complication in CAPD patients. Dialysis vintage, dialysis exchanges, urine output, serum albumin, serum creatinine, hyperphosphatemia knowledge behavior, and social support were the associated factors of hyperphosphatemia in CAPD patients. It is crucial for healthcare providers to maintain phosphorus balance among CAPD patients using phosphorus management strategies.