ArticlePhilosophical transactions of the Royal Society of London. Series B, Biological sciences2023
Remodelling and dysfunction of the sinus node in pulmonary arterial hypertension.
Article in Philosophical transactions of the Royal Society of London. Series B, Biological sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
What it found
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Who cites it
10 citing papers in PubMed, 9 citations in OpenAlex.
- Mechanisms and Advances in the Treatment of Arrhythmias Associated With Pulmonary Hypertension.Reviews in cardiovascular medicine · 2026Review
- Initial Body Weight as an Important Factor for Improving the Reliability and Translational Relevance of the Preclinical Monocrotaline-Induced Rat Pulmonary Hypertension Model.International journal of molecular sciences · 2025Article
- Review of D-Shape Left Ventricle Seen on Magnetic Resonance Imaging (MRI) or Computed Tomography (CT), Similar to the Movahed Sign Seen on Cardiac Gated Single-Photon Emission Computed Tomography (SPECT) as an Indicator for Right Ventricular Overload.Journal of clinical medicine · 2025Article
- Bradycardias in Patients with Pulmonary Hypertension-Prevalence, Pathophysiology and Clinical Relevance.Journal of cardiovascular development and disease · 2025Article
- Establishment of a prediction model of pulmonary artery hypertension in patients with hyperthyroidism.Annals of noninvasive electrocardiology : the official journal of the International Society for Holter and Noninvasive Electrocardiology, Inc · 2024Article
- Mitochondrial dysfunction is a key link involved in the pathogenesis of sick sinus syndrome: a review.Frontiers in cardiovascular medicine · 2024Review
- Genes Selectively Expressed in Rat Organs.Current genomics · 2024Article
- Cardiac arrhythmogenesis: roles of ion channels and their functional modification.Frontiers in physiology · 2024Review
- Article
- Cardiomyocyte electrophysiology and its modulation: current views and future prospects.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2023Review
Corrections and comments
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Authors and funding
14 authors at 5 institutions in 3 countries.
Funding
Abstract
Patients with pulmonary arterial hypertension (PAH) have a high burden of arrhythmias, including arrhythmias arising from sinus node dysfunction, and the aim of this study was to investigate the effects of PAH on the sinus node. In the rat, PAH was induced by an injection of monocrotaline. Three weeks after injection, there was a decrease of the intrinsic heart rate (heart rate in the absence of autonomic tone) as well as the normal heart rate, evidence of sinus node dysfunction. In the sinus node of PAH rats, there was a significant downregulation of many ion channels and Ca
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Registered trials
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