Evidence map›Paper›PMID 37122216›Full record

ArticlePhilosophical transactions of the Royal Society of London. Series B, Biological sciences2023

Non-canonical role of the sympathetic nervous system in the day-night rhythm in heart rate.

Cali Anderson, Gabriella Forte, Wei Hu, Henggui Zhang, Mark R Boyett, Alicia D'Souza

Open access · hybridAbstract read
In one paragraph

Article in Philosophical transactions of the Royal Society of London. Series B, Biological sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
3.7field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 17 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Article
  6. Twenty-Four Hour Rhythms in Cardiovascular Physiology.Acta physiologica (Oxford, England) · 2025
    Review
  7. Circadian influences on sudden cardiac death and cardiac electrophysiology.Journal of molecular and cellular cardiology · 2025
    Review
  8. Article
  9. Article
  10. Review
  11. Review
  12. Non-canonical role of the sympathetic nervous system in the day-night rhythm in heart rate.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2023
    Article
  13. Cardiomyocyte electrophysiology and its modulation: current views and future prospects.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2023
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Cali AndersonDivision of Cardiovascular Sciences, University of Manchester, 46 Grafton Street, Manchester M13 9NT, UK.
Gabriella ForteDivision of Cardiovascular Sciences, University of Manchester, 46 Grafton Street, Manchester M13 9NT, UK.
Wei HuDepartment of Physics and Astronomy, University of Manchester, Schuster Building, Brunswick Street, Manchester M13 9PL, UK.
Henggui ZhangDepartment of Physics and Astronomy, University of Manchester, Schuster Building, Brunswick Street, Manchester M13 9PL, UK.
Mark R BoyettFaculty of Life Sciences, University of Bradford, Richmond Road, Bradford BD7 1DP, UK.ORCID 0000-0003-3931-2020
Alicia D'SouzaDivision of Cardiovascular Sciences, University of Manchester, 46 Grafton Street, Manchester M13 9NT, UK.
University of Manchester · GBUniversity of Bradford · GB

Funding

British Heart Foundation FS/19/1/34035British Heart Foundation PG/15/16/31
6 · The paper itself

Abstract

Although, for many decades, the day-night rhythm in resting heart rate has been attributed to the parasympathetic branch of the autonomic nervous system (high vagal tone during sleep), recently we have shown that there is a circadian clock in the cardiac pacemaker, the sinus node, and the day-night rhythm in heart rate involves an intrinsic rhythmic transcriptional remodelling of pacemaker ion channels, particularly

Indexed as

Sinoatrial NodeSympathetic Nervous SystemAnimalsCircadian RhythmHeart RateIon ChannelsMiceSleepIon Channelscircadian rhythmheart ratepacemakingsinus nodesympathetic nervous system

Identifiers

PMID37122216
PMCPMC10150211
OpenAlexW4367600437

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.