ArticleEuropean radiology experimental2023
Improved visualization of the bone-implant interface and osseointegration in ex vivo acetabular cup implants using photon-counting detector CT.
Article in European radiology experimental, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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10 citing papers in PubMed, 13 citations in OpenAlex.
- Evaluating osseointegration, bone remodeling and osteolysis after total wrist arthroplasty using photon-counting detector CT.Skeletal radiology · 2026Article
- Optimization of dental implant imaging using photon-counting detector computed tomography in oral and maxillofacial surgery: an ex vivo study.European radiology experimental · 2026Article
- Assessment of bone-implant interface image quality for in-vivo acetabular cup implants using photon-counting detector CT: Impact of tin pre-filtration.European journal of radiology open · 2025Article
- Higher bone cement volume in total knee arthroplasty lowers the risk of postoperative radiolucent lines.Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA · 2025Article
- Assessment of metal artifacts from titanium wrist prostheses: photon-counting versus energy-integrating detector CT.European radiology experimental · 2025Article
- Photon-counting detector CT: a disrupting innovation in medical imaging.European radiology experimental · 2025Article
- Finite Element Analysis of a 3D-Printed Acetabular Prosthesis for an Acetabular Defect According to the Paprosky Classification.Materials (Basel, Switzerland) · 2025Article
- Chances and challenges of photon-counting CT in musculoskeletal imaging.Skeletal radiology · 2024Review
- Photon-Counting Computed Tomography for Microstructural Imaging of Bone and Joints.Current osteoporosis reports · 2024Review
- Assessment of material identification and quantification in the presence of metals using spectral photon counting CT.PloS one · 2024Article
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Authors and funding
5 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundSuccessful osseointegration of joint replacement implants is required for long-term implant survival. Accurate assessment of osseointegration could enable clinical discrimination of failed implants from other sources of pain avoiding unnecessary surgeries. Photon-counting detector computed tomography (PCD-CT) provides improvements in image resolution compared to conventional energy-integrating detector CT (EID-CT), possibly allowing better visualization of bone-implant-interfaces and osseointegration. The aim of this study was to assess the quality of visualization of bone-implant-interfaces and osseointegration in acetabular cup implants, using PCD-CT compared with EID-CT.
methodsTwo acetabular implants (one cemented, one uncemented) retrieved during revision surgery were scanned using PCD-CT and EID-CT at equal radiation dose. Images were reconstructed using different reconstruction kernels and iterative strengths. Delineation of the bone-implant and bone-cement-interface as an indicator of osseointegration was scored subjectively for image quality by four radiologists on a Likert scale and assessed quantitatively.
resultsDelineation of bone-implant and bone-cement-interfaces was better with PCD-CT compared with EID-CT (p ≤ 0.030). The highest ratings were given for PCD-CT at sharper kernels for the cemented cup (PCD-CT, median 5, interquartile range 4.25-5.00 versus EID-CT, 3, 2.00-3.75, p < 0.001) and the uncemented cup (5, 4.00-5.00 versus 2, 2-2, respectively, p < 0.001). The bone-implant-interface was 35-42% sharper and the bone-cement-interface was 28-43% sharper with PCD-CT compared with EID-CT, depending on the reconstruction kernel.
conclusionsPCD-CT might enable a more accurate assessment of osseointegration of orthopedic joint replacement implants. KEY POINTS: • The bone-implant interface ex vivo showed superior visualization using photon-counting detector computed tomography (PCD-CT) compared to energy-integrating detector computed tomography. • Harder reconstruction kernels in PCD-CT provide sharper images with lower noise levels. • These improvements in imaging might make it possible to visualize osseointegration in vivo.
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