Evidence map›Paper›PMID 37121719›Full record

ArticleInternal medicine (Tokyo, Japan)2023

Severe Erythroderma Due to Adult-onset Still's Disease-like Disease Related to Graft-versus-host Disease after Allogeneic Hematopoietic Stem Cell Transplantation.

Akiko Teramoto-Shibuya, Kaoru Funamizu, Naoki Sawa, Atsuhiko Suenaga, Yuki Oba, Daisuke Ikuma, Masayuki Yamanouchi, Eiko Hasegawa, Akinari Sekine, Tatsuya Suwabe and 9 more

Open access · diamondAbstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Internal medicine (Tokyo, Japan), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.6field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors at 2 institutions in 1 country.

Akiko Teramoto-ShibuyaDepartment of Rheumatology and Okinaka Memorial Institute for Medical Research, Toranomon Hospital, Japan.
Kaoru FunamizuDepartment of Dermatology, Toranomon Hospital, Japan.
Naoki SawaDepartment of Rheumatology and Okinaka Memorial Institute for Medical Research, Toranomon Hospital, Japan.
Atsuhiko SuenagaDepartment of Rheumatology and Okinaka Memorial Institute for Medical Research, Toranomon Hospital, Japan.
Yuki ObaDepartment of Rheumatology and Okinaka Memorial Institute for Medical Research, Toranomon Hospital, Japan.
Daisuke IkumaDepartment of Rheumatology and Okinaka Memorial Institute for Medical Research, Toranomon Hospital, Japan.
Masayuki YamanouchiDepartment of Rheumatology and Okinaka Memorial Institute for Medical Research, Toranomon Hospital, Japan.
Eiko HasegawaDepartment of Rheumatology and Okinaka Memorial Institute for Medical Research, Toranomon Hospital, Japan.
Akinari SekineDepartment of Rheumatology and Okinaka Memorial Institute for Medical Research, Toranomon Hospital, Japan.
Tatsuya SuwabeDepartment of Rheumatology and Okinaka Memorial Institute for Medical Research, Toranomon Hospital, Japan.
Kei KonoDepartment of Pathology, Toranomon Hospital, Japan.
Keiichi KinowakiDepartment of Pathology, Toranomon Hospital, Japan.
Takeshi FujiiDepartment of Pathology, Toranomon Hospital, Japan.
Tamiko TakemuraDepartment of Pathology, Kanagawa Cardiovascular and Respiratory Center, Japan.
Nobukazu HayashiDepartment of Dermatology, Toranomon Hospital, Japan.
Aya NishidaDepartment of Hematology, Toranomon Hospital, Japan.
Yuki MoriDepartment of Hematology, Toranomon Hospital, Japan.
Atsushi WakeDepartment of Hematology, Toranomon Hospital, Japan.
Yoshifumi UbaraDepartment of Rheumatology and Okinaka Memorial Institute for Medical Research, Toranomon Hospital, Japan.
Toranomon Hospital · JPKanagawa Cardiovascular and Respiratory Center · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A 35-year-old woman was treated with chemotherapy for leukemia. One year later, allogeneic hematopoietic stem cell transplantation (HSCT) was performed with umbilical cord blood. After nine months, she developed a spiking fever, sore throat, arthralgia, pleural effusion, hyperferritinemia, and persistent generalized pruritic erythema. A skin biopsy showed dyskeratotic cells in the epidermis, neutrophil infiltration in the epidermis and upper dermis, and neutrophils in the parakeratotic layer. Treatment with tocilizumab was effective. Adult-onset Still's disease (AOSD)-like disease related to graft versus-host disease (GVHD) after HSCT was suspected. Abnormal immune states related to GVHD may cause AOSD-like disease with more severe skin lesions than usual.

Indexed as

Dermatitis, ExfoliativeHematopoietic Stem Cell TransplantationStill's Disease, Adult-OnsetAdultErythemaFemaleHumansSkinadult-onset Still's diseaseallogeneic hematopoietic stem cell transplantationgraft-versus-host disease

Identifiers

PMID37121719
PMCPMC10208780
OpenAlexW4367556029

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.